ID E4NU97_HALBP Unreviewed; 810 AA.
AC E4NU97;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Copper/silver-translocating P-type ATPase {ECO:0000313|EMBL:ADQ68617.1};
GN OrderedLocusNames=Hbor_30810 {ECO:0000313|EMBL:ADQ68617.1};
GN ORFNames=C499_13535 {ECO:0000313|EMBL:ELY25510.1};
OS Halogeometricum borinquense (strain ATCC 700274 / DSM 11551 / JCM 10706 /
OS KCTC 4070 / PR3).
OG Plasmid pHBOR01 {ECO:0000313|EMBL:ADQ68617.1,
OG ECO:0000313|Proteomes:UP000006663}.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Halogeometricum.
OX NCBI_TaxID=469382 {ECO:0000313|EMBL:ADQ68617.1, ECO:0000313|Proteomes:UP000006663};
RN [1] {ECO:0000313|Proteomes:UP000006663}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700274 / DSM 11551 / JCM 10706 / KCTC 4070 / PR3
RC {ECO:0000313|Proteomes:UP000006663};
RC PLASMID=pHBOR01 {ECO:0000313|Proteomes:UP000006663};
RX PubMed=21304651; DOI=10.4056/sigs.23264;
RA Malfatti S., Tindall B.J., Schneider S., Fahnrich R., Lapidus A.,
RA Labuttii K., Copeland A., Glavina Del Rio T., Nolan M., Chen F., Lucas S.,
RA Tice H., Cheng J.F., Bruce D., Goodwin L., Pitluck S., Anderson I.,
RA Pati A., Ivanova N., Mavromatis K., Chen A., Palaniappan K.,
RA D'haeseleer P., Goker M., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P., Chain P.;
RT "Complete genome sequence of Halogeometricum borinquense type strain
RT (PR3).";
RL Stand. Genomic Sci. 1:150-159(2009).
RN [2] {ECO:0000313|EMBL:ADQ68617.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PR 3 {ECO:0000313|EMBL:ADQ68617.1};
RC PLASMID=pHBOR01 {ECO:0000313|EMBL:ADQ68617.1};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K.,
RA Mikhailova N., Anderson I., Brettin T., Detter J.C., Han C., Larimer F.,
RA Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T.,
RA Wu D., Tindal B., Klenk H.-P., Eisen J.A.;
RT "The complete plasmid1 of Halogeometricum borinquense DSM 11551.";
RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ELY25510.1, ECO:0000313|Proteomes:UP000011585}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11551 {ECO:0000313|EMBL:ELY25510.1,
RC ECO:0000313|Proteomes:UP000011585};
RX PubMed=25393412; DOI=10.1371/journal.pgen.1004784;
RA Becker E.A., Seitzer P.M., Tritt A., Larsen D., Krusor M., Yao A.I., Wu D.,
RA Madern D., Eisen J.A., Darling A.E., Facciotti M.T.;
RT "Phylogenetically driven sequencing of extremely halophilic archaea reveals
RT strategies for static and dynamic osmo-response.";
RL PLoS Genet. 10:E1004784-E1004784(2014).
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DR EMBL; CP001691; ADQ68617.1; -; Genomic_DNA.
DR EMBL; AOHT01000044; ELY25510.1; -; Genomic_DNA.
DR AlphaFoldDB; E4NU97; -.
DR KEGG; hbo:Hbor_30810; -.
DR PATRIC; fig|469382.19.peg.2672; -.
DR HOGENOM; CLU_001771_0_3_2; -.
DR OrthoDB; 8588at2157; -.
DR Proteomes; UP000006663; Plasmid pHBOR01.
DR Proteomes; UP000011585; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0019829; F:ATPase-coupled monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd00371; HMA; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR006121; HMA_dom.
DR InterPro; IPR036163; HMA_dom_sf.
DR InterPro; IPR027256; P-typ_ATPase_IB.
DR InterPro; IPR001757; P_typ_ATPase.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01511; ATPase-IB1_Cu; 1.
DR NCBIfam; TIGR01525; ATPase-IB_hvy; 1.
DR NCBIfam; TIGR01494; ATPase_P-type; 1.
DR PANTHER; PTHR43520; ATP7, ISOFORM B; 1.
DR PANTHER; PTHR43520:SF8; COPPER-TRANSPORTING ATPASE 2; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00403; HMA; 1.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00120; HATPASE.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF55008; HMA, heavy metal-associated domain; 1.
DR SUPFAM; SSF81660; Metal cation-transporting ATPase, ATP-binding domain N; 1.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
DR PROSITE; PS50846; HMA_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Plasmid {ECO:0000313|EMBL:ADQ68617.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006663};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 178..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..453
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 459..478
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 770..794
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 95..161
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 810 AA; 84748 MW; 081AF425C574526D CRC64;
MISDVSTDSP VVRSESPDAE SDACSLCELP TPAEPFTADD VDGAYCCRGC LEVSRALGGP
ERAAESDIEQ SLAAATDADD VPAATDADDV PDDAARTFLS VDGMHCATCE TFIESTAVGD
DGVYAAEASY ATDMLRVTYD PDETDLDGLV GRLGRYGYDA TDPDAAAETD EGSGLAKFLI
GGGVFGMMVM VWYVLFLYPT YLGFDPVVDL GAFDGLYVVA NVWVMSSIVL FYTGYPILRG
AYVSLAARQP NMDLLVALAA VAAYVFSVGS MVVGRTHVYF DVSVAIVLVV TLGNYYEDRI
KRRAATRLTD LTSARVTDAT RLSDDGRTES VPVESIRPDD RILVRPGERV PVDGVVVEGR
AAVDESLVTG ESIPTTREPG DSVIGGSVVT DDALTVEVGD DATSTLDRLV ELLWEIQSSR
GGAQRLADKL ATVFVPLVLA LSVLTTAGFL VLGSSPTDAL LNGLTVLIVS CPCALGLATP
LAVASGVRDA ADSGVVVASD AVFEDAPDAD TIIFDKTGTL TDGRMRVRGV TTAAADETTA
LELAAAVERY ASHPLAEALV QCAPDRLPTV TDSTVHQRGV TGRVDGTDIV VGHPSLLREA
GVTVPDELAS AGESVRDAGR VPVFVGWDRS ARAVFDVGDA PREMWDETLS ELGAERELVV
LTGDDERAAA QFRSHPAVDE VFAGVPPEAK AETVERFRSR GTVAMVGDGS NDAPALAAAD
VGIAFGSGTD LAGSAADAII VERGLDTVPT VFSVAAGTHR RIRENLAWAF VYNLVAIPLA
ISGLINPLLA AVAMGTSSLL VVVNSARSVE
//
