ID   E4PGG0_MARAH            Unreviewed;       418 AA.
AC   E4PGG0;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   SubName: Full=Xanthine/uracil permease {ECO:0000313|EMBL:ADP98071.1};
GN   OrderedLocusNames=HP15_2307 {ECO:0000313|EMBL:ADP98071.1};
OS   Marinobacter adhaerens (strain DSM 23420 / HP15).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC   Marinobacteraceae; Marinobacter.
OX   NCBI_TaxID=225937 {ECO:0000313|EMBL:ADP98071.1, ECO:0000313|Proteomes:UP000007077};
RN   [1] {ECO:0000313|EMBL:ADP98071.1, ECO:0000313|Proteomes:UP000007077}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23420 / HP15 {ECO:0000313|Proteomes:UP000007077};
RX   PubMed=21304739;
RA   Gardes A., Kaeppel E., Shehzad A., Seebah S., Teeling H., Yarza P.,
RA   Glockner F.O., Grossart H.P., Ullrich M.S.;
RT   "Complete genome sequence of Marinobacter adhaerens type strain (HP15), a
RT   diatom-interacting marine microorganism.";
RL   Stand. Genomic Sci. 3:97-107(2010).
RN   [2] {ECO:0000313|Proteomes:UP000007077}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 23420 / HP15 {ECO:0000313|Proteomes:UP000007077};
RA   Gaerdes A.A.M., Kaeppel E., Shezad A., Seebah S., Teeling H., Yarza P.,
RA   Gloeckner F.O., Ullrich M.S.;
RT   "Complete genome sequence of Marinobacter adhaerens type strain (HP15).";
RL   Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR   EMBL; CP001978; ADP98071.1; -; Genomic_DNA.
DR   RefSeq; WP_014577620.1; NC_017506.1.
DR   AlphaFoldDB; E4PGG0; -.
DR   STRING; 225937.HP15_2307; -.
DR   KEGG; mad:HP15_2307; -.
DR   PATRIC; fig|225937.3.peg.2328; -.
DR   eggNOG; COG2233; Bacteria.
DR   HOGENOM; CLU_017959_1_2_6; -.
DR   Proteomes; UP000007077; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR   InterPro; IPR006043; NCS2.
DR   InterPro; IPR006042; Xan_ur_permease.
DR   NCBIfam; TIGR00801; ncs2; 1.
DR   PANTHER; PTHR11119:SF3; LD30822P; 1.
DR   PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        12..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        45..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        87..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        116..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        157..174
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        181..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        221..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        304..326
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        332..353
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        365..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   418 AA;  43933 MW;  EB8DE960521EB53D CRC64;
     MQDHNNDPVW KQAIAGSQML LVAFGALVLM PLITGLDPNV ALFTAGLGTL IFHVVTGGQI
     PIFLASSFAF IAPVIASKGK FGMEETLGGL MAAGILYIFL SGLVRLRGTG FVRRLLPPVV
     IGPVIMTIGL GLAPVAVHMA SGRTGDGANQ LIPYDTAIWI AMISLAVTII MSVWSKGIFR
     LIPIMFGVIT GYILSAFAGI VDTTPIRDAA WFAVPNFVAP EFSWGAVLFM IPVAIAPAIE
     HIGDVLAIGN VTRKNYLEKP GLHRTLLGDG LATSAASMLG GPPNTTYSEV TGAVMLTKNF
     NPKVMWWAAC IAIVLAFVGK FGAALQTIPV PVMGGILCLL FGSIAVVGLN TLIRHQVDLS
     QSRNLVIVGV TLVFGIGGMV LGHLEGIALC AVAAIILNLI LPGSREAWGK AVYEQKAD
//