ID E4PRY1_MARAH Unreviewed; 505 AA.
AC E4PRY1;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Deoxyribodipyrimidine photolyase {ECO:0000313|EMBL:ADQ00016.1};
GN OrderedLocusNames=HP15_p187g19 {ECO:0000313|EMBL:ADQ00016.1};
OS Marinobacter adhaerens (strain DSM 23420 / HP15).
OG Plasmid pHP-187 {ECO:0000313|EMBL:ADQ00016.1,
OG ECO:0000313|Proteomes:UP000007077}.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Marinobacteraceae; Marinobacter.
OX NCBI_TaxID=225937 {ECO:0000313|EMBL:ADQ00016.1, ECO:0000313|Proteomes:UP000007077};
RN [1] {ECO:0000313|EMBL:ADQ00016.1, ECO:0000313|Proteomes:UP000007077}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23420 / HP15 {ECO:0000313|Proteomes:UP000007077};
RC PLASMID=Plasmid pHP-187 {ECO:0000313|Proteomes:UP000007077};
RX PubMed=21304739;
RA Gardes A., Kaeppel E., Shehzad A., Seebah S., Teeling H., Yarza P.,
RA Glockner F.O., Grossart H.P., Ullrich M.S.;
RT "Complete genome sequence of Marinobacter adhaerens type strain (HP15), a
RT diatom-interacting marine microorganism.";
RL Stand. Genomic Sci. 3:97-107(2010).
RN [2] {ECO:0000313|Proteomes:UP000007077}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23420 / HP15 {ECO:0000313|Proteomes:UP000007077};
RC PLASMID=Plasmid pHP-187 {ECO:0000313|Proteomes:UP000007077};
RA Gaerdes A.A.M., Kaeppel E., Shezad A., Seebah S., Teeling H., Yarza P.,
RA Gloeckner F.O., Ullrich M.S.;
RT "Complete genome sequence of Marinobacter adhaerens type strain (HP15).";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate;
CC Xref=ChEBI:CHEBI:15636; Evidence={ECO:0000256|ARBA:ARBA00001932};
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|PIRSR:PIRSR602081-1};
CC Note=Binds 1 FAD per subunit. {ECO:0000256|PIRSR:PIRSR602081-1};
CC -!- SIMILARITY: Belongs to the DNA photolyase class-1 family.
CC {ECO:0000256|ARBA:ARBA00005862}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001980; ADQ00016.1; -; Genomic_DNA.
DR RefSeq; WP_014579305.1; NC_017507.1.
DR AlphaFoldDB; E4PRY1; -.
DR KEGG; mad:HP15_p187g19; -.
DR PATRIC; fig|225937.3.peg.4258; -.
DR HOGENOM; CLU_010348_7_1_6; -.
DR Proteomes; UP000007077; Plasmid pHP-187.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.80; -; 1.
DR Gene3D; 1.10.579.10; DNA Cyclobutane Dipyrimidine Photolyase, subunit A, domain 3; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR InterPro; IPR036134; Crypto/Photolyase_FAD-like_sf.
DR InterPro; IPR036155; Crypto/Photolyase_N_sf.
DR InterPro; IPR005101; Cryptochr/Photolyase_FAD-bd.
DR InterPro; IPR002081; Cryptochrome/DNA_photolyase_1.
DR InterPro; IPR006050; DNA_photolyase_N.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR11455; CRYPTOCHROME; 1.
DR PANTHER; PTHR11455:SF9; CRYPTOCHROME-1; 1.
DR Pfam; PF00875; DNA_photolyase; 1.
DR Pfam; PF03441; FAD_binding_7; 1.
DR SUPFAM; SSF48173; Cryptochrome/photolyase FAD-binding domain; 1.
DR SUPFAM; SSF52425; Cryptochrome/photolyase, N-terminal domain; 1.
DR PROSITE; PS51645; PHR_CRY_ALPHA_BETA; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR602081-1};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630, ECO:0000256|PIRSR:PIRSR602081-
KW 1}; Lyase {ECO:0000313|EMBL:ADQ00016.1};
KW Plasmid {ECO:0000313|EMBL:ADQ00016.1}.
FT DOMAIN 1..133
FT /note="Photolyase/cryptochrome alpha/beta"
FT /evidence="ECO:0000259|PROSITE:PS51645"
FT BINDING 218
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
FT BINDING 279
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR602081-1"
SQ SEQUENCE 505 AA; 57351 MW; E15039802F7BC610 CRC64;
MQVFLLKRNL RLQDSDPFYE AMRGYRRFGP VLPLYIHEPS IIRQPDICLQ HQNFIFETLD
ELSQEIRSIG GKLLELVGEA VPTLDVIHQI APIARICTHQ ETTQGVQYER DKAVRKWCSR
NSVKLVEFQQ DGVVRAGCRD QKKQTFPEYF ADSVNRELKD PGGIDLGVRF ASTPLPSAPR
VTIPRAQGYD RPFRQRGGRS EAEKLFKDFF SVGSINSYPF KLSSPNTAWE GCSRISAYLS
YGIVSDRAVM KAIDDVVSSG HSYMDAAAFE KLQGRARFYL DRLMWRRNYL QMFEDDPTLE
HRHALSQFDG VRISDREDPL FKAWQSGRTG FPFIDACVRC LKETGWLNMR GRAAITSFAT
MNLWHDSLNV AAFLAGEFLD YMPGIHWPII QVVSGTASPQ NGIMVYCPMK QALDHDKDGV
FIRKYVPELS DLQAPHIHDL SRTTNHLSDL ARRSGFLPYP APIVDHIATA RVAKKRVSYL
QKGKVEVLSQ DHESSSTSSV QLGLL
//
