ID E4RKV2_HALHG Unreviewed; 428 AA.
AC E4RKV2;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Iron-containing alcohol dehydrogenase {ECO:0000313|EMBL:ADQ15693.1};
GN OrderedLocusNames=Halsa_2285 {ECO:0000313|EMBL:ADQ15693.1};
OS Halanaerobium hydrogeniformans (Halanaerobium sp. (strain sapolanicus)).
OC Bacteria; Bacillota; Clostridia; Halanaerobiales; Halanaerobiaceae;
OC Halanaerobium.
OX NCBI_TaxID=656519 {ECO:0000313|EMBL:ADQ15693.1, ECO:0000313|Proteomes:UP000007434};
RN [1] {ECO:0000313|EMBL:ADQ15693.1, ECO:0000313|Proteomes:UP000007434}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=sapolanicus {ECO:0000313|Proteomes:UP000007434};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N.,
RA Begemann M.B., Mormile M.R., Wall J.D., Elias D.A., Woyke T.;
RT "Complete sequence of Halanaerobium sp. sapolanicus.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADQ15693.1, ECO:0000313|Proteomes:UP000007434}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=sapolanicus {ECO:0000313|Proteomes:UP000007434};
RX PubMed=21602336; DOI=10.1128/JB.05209-11;
RA Brown S.D., Begemann M.B., Mormile M.R., Wall J.D., Han C.S., Goodwin L.A.,
RA Pitluck S., Land M.L., Hauser L.J., Elias D.A.;
RT "Complete Genome Sequence of the Haloalkaliphilic, Hydrogen Producing
RT Halanaerobium hydrogenoformans.";
RL J. Bacteriol. 193:3682-3683(2011).
CC -!- SIMILARITY: Belongs to the iron-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00007358}.
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DR EMBL; CP002304; ADQ15693.1; -; Genomic_DNA.
DR RefSeq; WP_013406757.1; NC_014654.1.
DR AlphaFoldDB; E4RKV2; -.
DR STRING; 656519.Halsa_2285; -.
DR KEGG; has:Halsa_2285; -.
DR eggNOG; COG1454; Bacteria.
DR HOGENOM; CLU_007207_0_0_9; -.
DR OrthoDB; 9804734at2; -.
DR Proteomes; UP000007434; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd08188; PDDH; 1.
DR Gene3D; 3.40.50.1970; -; 1.
DR Gene3D; 1.20.1090.10; Dehydroquinate synthase-like - alpha domain; 2.
DR InterPro; IPR001670; ADH_Fe/GldA.
DR InterPro; IPR018211; ADH_Fe_CS.
DR InterPro; IPR039697; Alcohol_dehydrogenase_Fe.
DR PANTHER; PTHR11496; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR11496:SF102; ALCOHOL DEHYDROGENASE 4; 1.
DR Pfam; PF00465; Fe-ADH; 2.
DR SUPFAM; SSF56796; Dehydroquinate synthase-like; 2.
DR PROSITE; PS00913; ADH_IRON_1; 1.
DR PROSITE; PS00060; ADH_IRON_2; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000007434}.
FT DOMAIN 10..340
FT /note="Alcohol dehydrogenase iron-type/glycerol
FT dehydrogenase GldA"
FT /evidence="ECO:0000259|Pfam:PF00465"
FT DOMAIN 341..420
FT /note="Alcohol dehydrogenase iron-type/glycerol
FT dehydrogenase GldA"
FT /evidence="ECO:0000259|Pfam:PF00465"
SQ SEQUENCE 428 AA; 46605 MW; 507029132A5A55A9 CRC64;
MSDYYDYMLP TVNFMGPGCV EVVGERCKIL GAKKVLIVTD SFLRNMEGGP VDQVVKYLKK
ANLNYAFYDE VEPNPKDVNV YAGLKIYERE NCDMIVTIGG GSAHDCGKAI GVAATHDGDL
YKDYAGIEKL ENETPPMVCV NTTAGTASEV TRHTVITDTS QTPNVKFVIV SWRNTPDVSI
NDPELMVGKP PGLTAATGMD ALTHAVETYV STNANALTDA AAIKSIELVA NNLRKVVKDG
QDIKARENMA NASVLSGFAF NNGGLGYVHA MAHQLGGFYD MPHGIANAIL LPYVEKFNLG
TDVERFSNIT EIFGKEQSKI SNNPEAQESI KAIKDEIDKL KRFKKIAEVF GVDTSNMSTR
EAAEASLDAI KELARDIGIP SSLSESKFDV KRDDFEEMAK LALEDGNAGT NPRKGSVEDI
VRIFEDAF
//
