ID E4RN40_HALHG Unreviewed; 462 AA.
AC E4RN40;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Hydroxyacylglutathione hydrolase {ECO:0000313|EMBL:ADQ14257.1};
GN OrderedLocusNames=Halsa_0810 {ECO:0000313|EMBL:ADQ14257.1};
OS Halanaerobium hydrogeniformans (Halanaerobium sp. (strain sapolanicus)).
OC Bacteria; Bacillota; Clostridia; Halanaerobiales; Halanaerobiaceae;
OC Halanaerobium.
OX NCBI_TaxID=656519 {ECO:0000313|EMBL:ADQ14257.1, ECO:0000313|Proteomes:UP000007434};
RN [1] {ECO:0000313|EMBL:ADQ14257.1, ECO:0000313|Proteomes:UP000007434}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=sapolanicus {ECO:0000313|Proteomes:UP000007434};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N.,
RA Begemann M.B., Mormile M.R., Wall J.D., Elias D.A., Woyke T.;
RT "Complete sequence of Halanaerobium sp. sapolanicus.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADQ14257.1, ECO:0000313|Proteomes:UP000007434}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=sapolanicus {ECO:0000313|Proteomes:UP000007434};
RX PubMed=21602336; DOI=10.1128/JB.05209-11;
RA Brown S.D., Begemann M.B., Mormile M.R., Wall J.D., Han C.S., Goodwin L.A.,
RA Pitluck S., Land M.L., Hauser L.J., Elias D.A.;
RT "Complete Genome Sequence of the Haloalkaliphilic, Hydrogen Producing
RT Halanaerobium hydrogenoformans.";
RL J. Bacteriol. 193:3682-3683(2011).
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DR EMBL; CP002304; ADQ14257.1; -; Genomic_DNA.
DR RefSeq; WP_013405348.1; NC_014654.1.
DR AlphaFoldDB; E4RN40; -.
DR STRING; 656519.Halsa_0810; -.
DR KEGG; has:Halsa_0810; -.
DR eggNOG; COG0491; Bacteria.
DR eggNOG; COG0607; Bacteria.
DR HOGENOM; CLU_030571_7_1_9; -.
DR OrthoDB; 9800872at2; -.
DR Proteomes; UP000007434; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0050313; F:sulfur dioxygenase activity; IEA:InterPro.
DR GO; GO:0006749; P:glutathione metabolic process; IEA:InterPro.
DR CDD; cd07724; POD-like_MBL-fold; 1.
DR CDD; cd00158; RHOD; 2.
DR Gene3D; 3.40.250.10; Rhodanese-like domain; 2.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR044528; POD-like_MBL-fold.
DR InterPro; IPR001763; Rhodanese-like_dom.
DR InterPro; IPR036873; Rhodanese-like_dom_sf.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR43084; PERSULFIDE DIOXYGENASE ETHE1; 1.
DR PANTHER; PTHR43084:SF1; PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR Pfam; PF00581; Rhodanese; 2.
DR SMART; SM00849; Lactamase_B; 1.
DR SMART; SM00450; RHOD; 2.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR SUPFAM; SSF52821; Rhodanese/Cell cycle control phosphatase; 2.
DR PROSITE; PS50206; RHODANESE_3; 2.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:ADQ14257.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007434}.
FT DOMAIN 261..350
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
FT DOMAIN 367..455
FT /note="Rhodanese"
FT /evidence="ECO:0000259|PROSITE:PS50206"
SQ SEQUENCE 462 AA; 52109 MW; 0C73A6ECED419D8D CRC64;
MFYKKISSKG LAHFSYLIGD ENEAAVIDPR RDIDVYLKEA EKEGTEIKYI FETHRNEDYI
IGSRALASVT GAEIFHADGQ LAYQYENTVE AGKKYKLGRL NLEAMHTPGH TKGSHSYILN
DYDDQPWMIF TGDILFANDV GRIDFYGEEN IPEIAALLYD SLYNKIMPLG DGVIICPAHG
AGSVCGSQIA DREITTIGIE KKSNPYLQYK SKEEFVSEVG EMEEKPQYFK AMEAANLEAP
ARTELPFVKP LKPGEFEEKA AQKDYVVIDI RSESDFASAH VPSALYLRDN ILASFIGWFM
PTDKKILLVN DGSYPEETIR TLYRMGYEKI EGYLYRGMLS WNMAGKDSNS ISAVNISEFC
DFVKDKNKDE YLLLDIRKEE EKEEEGYLES AKEIPLNDLQ ADLNNYLAEL ENKKDIYVFC
GSGIRSMTAA SLINAHLEAD VKVVLGGLTA WSASKCLLKI KK
//
