ID E4U2T5_SULKY Unreviewed; 554 AA.
AC E4U2T5;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Fumarate reductase/succinate dehydrogenase flavoprotein domain protein {ECO:0000313|EMBL:ADR33670.1};
GN OrderedLocusNames=Sulku_1007 {ECO:0000313|EMBL:ADR33670.1};
OS Sulfuricurvum kujiense (strain ATCC BAA-921 / DSM 16994 / JCM 11577 /
OS YK-1).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Sulfurimonadaceae; Sulfuricurvum.
OX NCBI_TaxID=709032 {ECO:0000313|EMBL:ADR33670.1, ECO:0000313|Proteomes:UP000008721};
RN [1] {ECO:0000313|EMBL:ADR33670.1, ECO:0000313|Proteomes:UP000008721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-921 / DSM 16994 / JCM 11577 / YK-1
RC {ECO:0000313|Proteomes:UP000008721};
RX PubMed=22675602; DOI=10.4056/sigs.2456004;
RA Han C., Kotsyurbenko O., Chertkov O., Held B., Lapidus A., Nolan M.,
RA Lucas S., Hammon N., Deshpande S., Cheng J.F., Tapia R., Goodwin L.A.,
RA Pitluck S., Liolios K., Pagani I., Ivanova N., Mavromatis K.,
RA Mikhailova N., Pati A., Chen A., Palaniappan K., Land M., Hauser L.,
RA Chang Y.J., Jeffries C.D., Brambilla E.M., Rohde M., Spring S.,
RA Sikorski J., Goker M., Woyke T., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P., Detter J.C.;
RT "Complete genome sequence of the sulfur compounds oxidizing
RT chemolithoautotroph Sulfuricurvum kujiense type strain (YK-1(T)).";
RL Stand. Genomic Sci. 6:94-103(2012).
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DR EMBL; CP002355; ADR33670.1; -; Genomic_DNA.
DR RefSeq; WP_013459867.1; NC_014762.1.
DR AlphaFoldDB; E4U2T5; -.
DR STRING; 709032.Sulku_1007; -.
DR KEGG; sku:Sulku_1007; -.
DR eggNOG; COG1053; Bacteria.
DR HOGENOM; CLU_014312_6_2_7; -.
DR OrthoDB; 9806724at2; -.
DR Proteomes; UP000008721; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.20.58.100; Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR037099; Fum_R/Succ_DH_flav-like_C_sf.
DR InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR InterPro; IPR030664; SdhA/FrdA/AprA.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR PANTHER; PTHR11632; SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT; 1.
DR PANTHER; PTHR11632:SF51; SUCCINATE DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN SUBUNIT, MITOCHONDRIAL; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR Pfam; PF02910; Succ_DH_flav_C; 1.
DR PIRSF; PIRSF000171; SDHA_APRA_LASPO; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF46977; Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000008721}.
FT DOMAIN 4..368
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
FT DOMAIN 422..522
FT /note="Fumarate reductase/succinate dehydrogenase
FT flavoprotein-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02910"
FT ACT_SITE 267
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000171-1"
FT ACT_SITE 272
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR630664-50"
SQ SEQUENCE 554 AA; 60716 MW; 36EC525F40C28B83 CRC64;
MLYDVIVVGS GISGLYAALN ARRAGLHVAL VCKSNPLRSN SAVASGGINA VLKTTRNDSI
REHIADTLNG ADKLGRFSAA SAMAAGAGEI IEELQSLGVK FDTDENGAIA QRPFGGTKAK
RTCYIADRTG ASITQTLLVQ CRKEGVEIFQ NHVMLSIATF DGKLSGITLL RRRDSNVIAF
ACKSLVLAGG GFAGIYRGHS TNSQESSGDI LAIALRSKMR LVNMEFVQFH PTTLANSGTL
ISEAARGEGA YIVDENGVRF TDELQTRDKL SRDIVRHQLA GHTIYLDFRH LGEELIDKKL
PSARKHALNG AGIDICSELL PITPSAHYTM GGIWSRNDTS TDIPNVFVCG ECAYSGVHGA
NRLGGNSLLE AAYFGRLAGS EAATAAKKGV FHPIDYAIVA KELRYVESIL EGENRFNINT
MRRNLGNNLY NNAGVFRTHD SLANALEYVH YLMKMSSGLC CINKERNDNV ELLSIIEFRN
SLTVAEAMVM SALAREESRG SHYRNDFPEK DDKNYETNTI IRRLAKAFLR ISFESHLSSD
WWDRIRRLFH TQIG
//
