ID E4UQR5_ARTGP Unreviewed; 532 AA.
AC E4UQR5;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Abhydrolase domain-containing protein 4 {ECO:0000313|EMBL:EFR00083.1};
GN ORFNames=MGYG_03090 {ECO:0000313|EMBL:EFR00083.1};
OS Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum
OS gypseum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Nannizzia.
OX NCBI_TaxID=535722 {ECO:0000313|Proteomes:UP000002669};
RN [1] {ECO:0000313|Proteomes:UP000002669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4604 / CBS 118893 {ECO:0000313|Proteomes:UP000002669};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- SIMILARITY: Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.
CC {ECO:0000256|ARBA:ARBA00038097}.
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DR EMBL; DS989823; EFR00083.1; -; Genomic_DNA.
DR RefSeq; XP_003175565.1; XM_003175517.1.
DR AlphaFoldDB; E4UQR5; -.
DR STRING; 535722.E4UQR5; -.
DR GeneID; 10030873; -.
DR VEuPathDB; FungiDB:MGYG_03090; -.
DR eggNOG; KOG4409; Eukaryota.
DR HOGENOM; CLU_017361_3_0_1; -.
DR InParanoid; E4UQR5; -.
DR OMA; HLYLDGW; -.
DR OrthoDB; 276964at2759; -.
DR Proteomes; UP000002669; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR PANTHER; PTHR42886:SF29; PUMMELIG, ISOFORM A; 1.
DR PANTHER; PTHR42886; RE40534P-RELATED; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:EFR00083.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002669}.
FT DOMAIN 141..513
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF00561"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 68..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 258..292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 395..447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..292
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..415
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..441
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 532 AA; 58351 MW; 8F7B08261C738117 CRC64;
MASTVSAAEA RQASTASPAA EPPAQAKQPS SFFPLGYKEG FSQWWTCMPA ATAEHSVLSF
IPYLQQPPTH KQTGNEPAVP DGQADSLTTA DTSQAAQVSA NSVDDPYGPR RWRSSMVQLS
GDNRALNEFS VERVGEKVEN NLVVLHGYGA GLGFFYKNFE SLSRAKGWQL YALDLLGMGR
STRPPFKIHA KERGQAVTEA EDWFIDALEE WRVKRKIERF TLMGHSLGGY MAVAYALKYP
GRLDKLILAS PVGIPKDPRA VETDLTEPSE STLSAEFTQD QDATTTNNGL AARTPPLLRP
LPKWLTYLWD ANVSPFTFVR WSGPLGPRLV SGWTSRRFSH LPQPESKALH DYAYSIFRMR
GSGEYALSYI LAPGAYARKP LINRIHGVGR QLIREPVPSS ASQTSLSSAD SSASPQPSPS
PSPSATPSDT ASSTPSPGEQ QPVPRKENGI PVVLMYGDHD WMDVEGGHAA KKKIDEERER
ILKDATPEEK LADRGSAKVV VIKKAGHHIY LDGWEEFNKV ILDEMKATSN EG
//
