ID   E4USJ5_ARTGP            Unreviewed;       710 AA.
AC   E4USJ5;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Long-chain-fatty-acid-CoA ligase 5 {ECO:0000313|EMBL:EFR01346.1};
GN   ORFNames=MGYG_04353 {ECO:0000313|EMBL:EFR01346.1};
OS   Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum
OS   gypseum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Nannizzia.
OX   NCBI_TaxID=535722 {ECO:0000313|Proteomes:UP000002669};
RN   [1] {ECO:0000313|Proteomes:UP000002669}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4604 / CBS 118893 {ECO:0000313|Proteomes:UP000002669};
RX   PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA   Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA   Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA   Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA   Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA   Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT   "Comparative genome analysis of Trichophyton rubrum and related
RT   dermatophytes reveals candidate genes involved in infection.";
RL   MBio 3:E259-E259(2012).
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DR   EMBL; DS989824; EFR01346.1; -; Genomic_DNA.
DR   RefSeq; XP_003174176.1; XM_003174128.1.
DR   AlphaFoldDB; E4USJ5; -.
DR   STRING; 535722.E4USJ5; -.
DR   GeneID; 10029465; -.
DR   VEuPathDB; FungiDB:MGYG_04353; -.
DR   eggNOG; KOG1256; Eukaryota.
DR   HOGENOM; CLU_000022_45_4_1; -.
DR   InParanoid; E4USJ5; -.
DR   OMA; PRIWTKF; -.
DR   OrthoDB; 443463at2759; -.
DR   Proteomes; UP000002669; Unassembled WGS sequence.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   PANTHER; PTHR43272; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR   PANTHER; PTHR43272:SF3; LONG-CHAIN-FATTY-ACID--COA LIGASE 5; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Ligase {ECO:0000313|EMBL:EFR01346.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002669}.
FT   DOMAIN          70..513
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   710 AA;  78049 MW;  36F8B30AB89EE866 CRC64;
     MIFSSESPLK AAVAEYGQKP PKGTPESVPV PNSELPGRSK IYRHWKIGSK ELPKSIDPKV
     HTGHDMFESA ALLYPKRPCL GYRPWIPATK SYGPYVWMDY QTVQKRRAAI GVGLAELHER
     VGVQGRNYGV GLWCQNRPEW QLVDLACMSQ GIFTVSLYET LGPEATEFIV QNTELVSVAC
     SLPHVPTLLK LKPRLPSLKF IVCLEDLDSN EPQGHTKRDI LNPIAKELGV AIYTLNEVEE
     LGASLNRPYT LPSPDDIVTI NYTSGTTGLP KGVVLTHANA VAAASCSLST IPQGPGDVSC
     SYLPLAHIYG RLIEQALLWA GGQIGYFHGN ILELVDDFKL LRPTVLASVP RLYSRFGGAI
     RAATVEQPGF KGALSRHVVS TKTANLVDAK PQDATYTHSI YDRIWTKKVA AGLGFDRMKC
     MVSGSAPLDG SLHQFLRIAF GANIVQGYGL TESYAIATCQ AGHDLTSGHC GSVSIAQEAC
     LLSLPDMDYS VDDKPYPRGE LLLRGNTMFR EYFKNPEETA KAMTEDGWFR TGDVCQVDEF
     GRFHIIDRRK NLLKLAQGEY VSPERLEGIY QSSCPYVAQA FVHGDGVQSH LVAILGVQPD
     IFAPFASKVL KKNIAMEDTE ALKAAASDEK VVLAVLRDMD HAARANKLSG YEKVKNVALM
     VDPFSIDNGL LTPTLKLKRP QSVKMYRDVF DRLYAHTPDL SVAKRAKAKL
//