ID E4UWQ4_ARTGP Unreviewed; 491 AA.
AC E4UWQ4;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Decaprenyl-diphosphate synthase subunit 1 {ECO:0000313|EMBL:EFR02597.1};
GN ORFNames=MGYG_05594 {ECO:0000313|EMBL:EFR02597.1};
OS Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum
OS gypseum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Nannizzia.
OX NCBI_TaxID=535722 {ECO:0000313|Proteomes:UP000002669};
RN [1] {ECO:0000313|Proteomes:UP000002669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4604 / CBS 118893 {ECO:0000313|Proteomes:UP000002669};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR EMBL; DS989825; EFR02597.1; -; Genomic_DNA.
DR RefSeq; XP_003173008.1; XM_003172960.1.
DR AlphaFoldDB; E4UWQ4; -.
DR STRING; 535722.E4UWQ4; -.
DR GeneID; 10028285; -.
DR VEuPathDB; FungiDB:MGYG_05594; -.
DR eggNOG; KOG0776; Eukaryota.
DR HOGENOM; CLU_014015_1_0_1; -.
DR InParanoid; E4UWQ4; -.
DR OMA; AFDYYLH; -.
DR OrthoDB; 25272at2759; -.
DR Proteomes; UP000002669; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0046165; P:alcohol biosynthetic process; IEA:UniProt.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR GO; GO:0043386; P:mycotoxin biosynthetic process; IEA:UniProt.
DR GO; GO:1901663; P:quinone biosynthetic process; IEA:UniProt.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001:SF69; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000002669};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 491 AA; 53555 MW; 37B4A6C13330901A CRC64;
MRARASLPAY GLSLRASQTF RPASICSRCL HSRFAISLSI PPAHITARNY HPSRRKDQSA
LASAMSAAQN LFSKEISKAP PPPLPSNPGS LPANVSVDPL RMVGKELKFL KKNLRSLLGS
GHPILDQVAK YYAQSEGKQV RPMLVLLMSQ ATALTPSCEK RRERDQLLSS LLSTPSSSSS
GAYINDSINS PAILADTNPD LMPLSSPTRD TVYAPTKEDS KDDFANVLPS QRRLAEITEL
IHTASLLHDD VIDNAVTRRS NLSANLAFGN KMAVLAGDFL LGRASVFIAR LRDPEVIELL
GTVMANLVEG EFMQLKNTML DESNPVWSED IISYYLQKTY LKSASLISKS CRAAALLNQS
GPEVAEAAYL FGRNLGLAFQ LVDDMLDYTI SGEELGKPAG ADLELGLATS PLLFAWKQRP
ELGKLVGRKF SREGDVQLAR QIVAQSDGLE QTRALAQQYA DDAVAAISKF PDSEAKDGLI
EICRKTINRR K
//
