ID E4UXS4_ARTGP Unreviewed; 433 AA.
AC E4UXS4;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Zinc-regulated transporter 1 {ECO:0000313|EMBL:EFR01969.1};
GN ORFNames=MGYG_04971 {ECO:0000313|EMBL:EFR01969.1};
OS Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum
OS gypseum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Nannizzia.
OX NCBI_TaxID=535722 {ECO:0000313|Proteomes:UP000002669};
RN [1] {ECO:0000313|Proteomes:UP000002669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4604 / CBS 118893 {ECO:0000313|Proteomes:UP000002669};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS989825; EFR01969.1; -; Genomic_DNA.
DR RefSeq; XP_003172380.1; XM_003172332.1.
DR AlphaFoldDB; E4UXS4; -.
DR STRING; 535722.E4UXS4; -.
DR GeneID; 10027649; -.
DR VEuPathDB; FungiDB:MGYG_04971; -.
DR eggNOG; KOG1558; Eukaryota.
DR HOGENOM; CLU_027089_1_2_1; -.
DR InParanoid; E4UXS4; -.
DR OMA; VGFMNAV; -.
DR OrthoDB; 1112460at2759; -.
DR Proteomes; UP000002669; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR003689; ZIP.
DR PANTHER; PTHR11040:SF60; FAMILY ZINC TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G04010)-RELATED; 1.
DR PANTHER; PTHR11040; ZINC/IRON TRANSPORTER; 1.
DR Pfam; PF02535; Zip; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002669};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 38..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 157..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 194..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 215..235
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 433 AA; 46532 MW; 3D87265049714DF3 CRC64;
MEAPALSGLD AIPLDKLKDE YLRRSCGSKK TNAYNTPAHV AALFLILALS TFACAFPIIA
RRFPKLPIPR RFLFLSRHFG TGVLIATAFV HLLPTAFISL TSPCLPRFWN KGYPAFAGLV
AMVAVLMVVC IEMFFAMKGA GHVHGSEYDT LIGDMHHDHD HGHGHENGSS VQMGKVRRKP
PARIVISAST ENLVDGASPL MPNGNGRAQL GGETTDPSDD EDLDIDLEEL DPQPDDNESV
LVHSRHQGHA HHHHRHHSHD NHMSEQSAQK QLLQCLLLEA GILFHSIFIG MALSVATGAN
FLVLLVAISF HQTFEGFALG ARIAALIPAL FPASSPKPWL MALAYGATTP IGQAIGLGVH
NLYDPASTTG LLMVGLTNAF SSGLLLFAGL VELLAEDFLS DRSYETLQGR NRLEAGIAVA
AGASLMALVG AFA
//
