ID   E4V843_BIFBI            Unreviewed;       860 AA.
AC   E4V843;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   24-JAN-2024, entry version 34.
DE   SubName: Full=Transglutaminase-like protein {ECO:0000313|EMBL:EFR49785.1};
GN   ORFNames=BBNG_00332 {ECO:0000313|EMBL:EFR49785.1};
OS   Bifidobacterium bifidum NCIMB 41171.
OC   Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC   Bifidobacteriaceae; Bifidobacterium.
OX   NCBI_TaxID=398513 {ECO:0000313|EMBL:EFR49785.1, ECO:0000313|Proteomes:UP000002776};
RN   [1] {ECO:0000313|EMBL:EFR49785.1, ECO:0000313|Proteomes:UP000002776}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCIMB 41171 {ECO:0000313|EMBL:EFR49785.1,
RC   ECO:0000313|Proteomes:UP000002776};
RG   The Broad Institute Genome Sequencing Platform;
RA   Goulas T., Tzortzis G., Gibson G.R., Ward D., Mehta T., Young S., Jaffe D.,
RA   Gnerre S., Berlin A., Heiman D., Hepburn T., Shea T., Sykes S.,
RA   Alvarado L., Kodira C., Borodovsky M., Lander E., Galagan J., Nusbaum C.,
RA   Birren B.;
RT   "Annotation of Bifidobacterium bifidum strain NCIMB 41171.";
RL   Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS990229; EFR49785.1; -; Genomic_DNA.
DR   AlphaFoldDB; E4V843; -.
DR   eggNOG; COG1305; Bacteria.
DR   HOGENOM; CLU_012121_2_0_11; -.
DR   Proteomes; UP000002776; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.10.620.30; -; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR002931; Transglutaminase-like.
DR   PANTHER; PTHR42736; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR   PANTHER; PTHR42736:SF1; PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE; 1.
DR   Pfam; PF01841; Transglut_core; 1.
DR   SMART; SM00460; TGc; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        42..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        66..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        94..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        158..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        184..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        208..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        232..257
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        670..691
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          513..595
FT                   /note="Transglutaminase-like"
FT                   /evidence="ECO:0000259|SMART:SM00460"
FT   REGION          599..644
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          810..860
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        627..641
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        810..825
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        828..860
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   860 AA;  91575 MW;  79FE8598009D8842 CRC64;
     MTGTGATTGS WAESTHSVIW LTRGGNRLPL ARVGRRSWGT NLISVAVIAL TSLIAASNLL
     DVYGSAAMWA VAAVPATLLG ALIAYAGTAP ALRLWWQIVF LIVAQGVIGP VIALNDTAIS
     HVIPSVETLS QGFVSTFGAF KYLIAVPPPT GSGDGSLMAA WTICLWLSFL AGVFAIGDKR
     QLSVLSLLPI AIELVVCALL GTQTGFQPIA SGVLIGLIMI VWLSWRWQLL ELGRWISATI
     ILLLAAGLGV GACMGIGQSR LILRDYYDPP LSPYDYASPL SGLRSYVKDH KDDTLLTVTN
     LPEGTPVRLA VMDQFDGNVW NLSDSTEASD SSDYRRVGTR IPNTVDGKKF TATFTIDKGL
     SDKWLPLAGA ASSVDVTSAG KTGGANGNGG GESRSSADHT LFYYNESTQS AIIPAGLSTG
     MTYTESGIIA PTPTDKEIAK ANAAVTNQPG TKDVPDSVGK FASSVAGGED TAGAQAQALV
     AQLKDSGWFS HGLTGDYPSL PGHGSYRINA LLAGSAMVGD SEQYASAMAL MARELGLPSR
     VVMGFLPKND DGDISNDRTE TVNGTSTVKF TGNDIEAWVE INLEGYGWVA FYPTPKETKI
     PDDNQNLTPP NPQTLVRQPP VPLTDPLRDE EQAHGKSALA GEDATDEPAA SIWSTIGRIA
     AKVAIYGSPV WIPLLICLLI LALKTVALAR LRRHGDARQR ITSGWQAVHA LAGQSGIPVT
     GTRRDQAQAI ARQLNIDGAP LIALGRQADY AAFSGQPVTP EQAGAYWRSV LTTRKLMLAS
     QSFMRRLRTR LSLRGVFHNV RILSSIRTWR HGDKRKPDGR QPAKQRPVKR KSSTQQPAGQ
     KPATQQPSAQ QPSSQKGRQS
//