ID   E4WVQ1_OIKDI            Unreviewed;       404 AA.
AC   E4WVQ1;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   RecName: Full=Cullin N-terminal domain-containing protein {ECO:0000259|Pfam:PF00888};
GN   ORFNames=GSOID_T00008959001 {ECO:0000313|EMBL:CBY21204.1};
OS   Oikopleura dioica (Tunicate).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC   Oikopleuridae; Oikopleura.
OX   NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY21204.1};
RN   [1] {ECO:0000313|EMBL:CBY21204.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21097902; DOI=10.1126/science.1194167;
RA   Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA   Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA   Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA   Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA   Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA   Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA   Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA   Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA   Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA   Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA   Roest Crollius H., Wincker P., Chourrout D.;
RT   "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT   pelagic tunicate.";
RL   Science 330:1381-1385(2010).
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019}.
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DR   EMBL; FN653017; CBY21204.1; -; Genomic_DNA.
DR   AlphaFoldDB; E4WVQ1; -.
DR   InParanoid; E4WVQ1; -.
DR   Proteomes; UP000001307; Unassembled WGS sequence.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 3.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF169; CULLIN-1; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001307}.
FT   DOMAIN          1..374
FT                   /note="Cullin N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00888"
SQ   SEQUENCE   404 AA;  46650 MW;  7541AC79D7C3BFCB CRC64;
     MHTYTKIFNY CTSTRSAISS IGRSSRVTSR TNRRPTGENG VNTANDMFIG GDLYKKLRNV
     IDDKVTCVYN KAKKVNGVDI LTDYHKNWKD YKFSIRVLNG VAQYLNKHWV QREKEEHGGP
     DSAVHDVHSM GIVAWRQNMY MKNLEPMMDQ IMRVIQKERE NEADNSHHLL LKTILQESVC
     ELGLEKNGEK GQNGRPERDL AVYRETFETR FLKETTQYYQ TESSSFIESH SLVDYLVKIE
     KRFEEEERRV RSYLDSSTGS KVEHTLVKVL IEAHIARIHD EFKPMVEHEK IDDLKRVFAL
     VNRADKFRSD ADKSNNVSPF LDPMRDAFRQ HVISEGIAAV DAIKESALAE PKTYIDAVLT
     VYKKYAKVVL DAFVFRVERT CHASHVELIA KLANNSFLFL NVSS
//