ID E4WX73_OIKDI Unreviewed; 548 AA.
AC E4WX73;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Bromo domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=GSOID_T00011502001 {ECO:0000313|EMBL:CBY21965.1};
OS Oikopleura dioica (Tunicate).
OC Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC Oikopleuridae; Oikopleura.
OX NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY21965.1};
RN [1] {ECO:0000313|EMBL:CBY21965.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21097902; DOI=10.1126/science.1194167;
RA Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA Roest Crollius H., Wincker P., Chourrout D.;
RT "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT pelagic tunicate.";
RL Science 330:1381-1385(2010).
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DR EMBL; FN653018; CBY21965.1; -; Genomic_DNA.
DR AlphaFoldDB; E4WX73; -.
DR InParanoid; E4WX73; -.
DR Proteomes; UP000001307; Unassembled WGS sequence.
DR Gene3D; 1.20.1270.220; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 2.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR027353; NET_dom.
DR InterPro; IPR038336; NET_sf.
DR PANTHER; PTHR22880:SF225; BROMODOMAIN-CONTAINING PROTEIN BET-1; 1.
DR PANTHER; PTHR22880; FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS; 1.
DR Pfam; PF17035; BET; 1.
DR Pfam; PF00439; Bromodomain; 2.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 2.
DR SUPFAM; SSF47370; Bromodomain; 2.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 2.
DR PROSITE; PS51525; NET; 1.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Reference proteome {ECO:0000313|Proteomes:UP000001307};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 25..97
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 251..323
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 423..505
FT /note="NET"
FT /evidence="ECO:0000259|PROSITE:PS51525"
FT REGION 120..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 344..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 398..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 502..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..177
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..207
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 351..367
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 407..421
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..532
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 533..548
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 548 AA; 62221 MW; C97C223EA3ED1FF9 CRC64;
MPEVKKYPMT NQLQYIKKHI FMTLWNHKFA WPFQKPVDPV ELNLPDYFTI IKNPMDMSTL
KKKLYGGQYE SAKQCIADYD LMFENCYNYN RPTDDISIMG KKIQDLLHTK CKNMPQVEAV
VEKQKRKKNP LDGLGVSGST PVGTRDRNPP TPMSIDPVPS PAPSSKSMNS ATDFESASIA
PSPGGPEMPQ LSAAPQKNGQ SAPTVRTRPN PPKRKTESIS SFDGPAKKSS MPKKKEMRVC
AAILRELHQK RHQQYAWPFY VPVDVKGLEL HDYYDVIKRP MDLSLAQKNI DNDMYNDKNE
FIADIMLIFE NCRAYNPPDH EVVQMANRLQ KVFEAKVAES FSSADAAANH SEESDFGDSD
SDDERGRKLQ QIQKKLREVQ EQLAYLMDLQ ARLVKAGKRK KKKGDMGAGK KGGNRDGEGA
IYDFDSDEDH KEMTYDEKRQ LSLDINRLPS DKLGRVVTII QNREAHYREH NPDEIEIDFD
TLKTATLREL DTYVSFCLKK KTSKQKAATP VIKKPDEKPK EEIKKKSSRL SDSSDDSSGS
DSSLSEAH
//
