ID   E4X582_OIKDI            Unreviewed;       543 AA.
AC   E4X582;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=Leucine-rich repeat-containing protein 63 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=GSOID_T00002312001 {ECO:0000313|EMBL:CBY18451.1};
OS   Oikopleura dioica (Tunicate).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC   Oikopleuridae; Oikopleura.
OX   NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY18451.1};
RN   [1] {ECO:0000313|EMBL:CBY18451.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21097902; DOI=10.1126/science.1194167;
RA   Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA   Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA   Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA   Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA   Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA   Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA   Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA   Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA   Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA   Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA   Roest Crollius H., Wincker P., Chourrout D.;
RT   "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT   pelagic tunicate.";
RL   Science 330:1381-1385(2010).
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DR   EMBL; FN653025; CBY18451.1; -; Genomic_DNA.
DR   AlphaFoldDB; E4X582; -.
DR   InParanoid; E4X582; -.
DR   Proteomes; UP000001307; Unassembled WGS sequence.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PANTHER; PTHR45752; LEUCINE-RICH REPEAT-CONTAINING; 1.
DR   PANTHER; PTHR45752:SF149; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 39; 1.
DR   Pfam; PF00560; LRR_1; 1.
DR   Pfam; PF13855; LRR_8; 1.
DR   SMART; SM00369; LRR_TYP; 4.
DR   SUPFAM; SSF52058; L domain-like; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001307};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REGION          1..78
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          195..222
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        19..33
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        58..74
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   543 AA;  62241 MW;  36B146CB8BEFFD37 CRC64;
     MVLLRRPRPA PPSPVPYEEP AETRKHERPR SPTSEMTNGD ASFHSKILHH RVTTTPVIKT
     RSDDNSSSKN TVQKPMEPAY KDQKLQQRSY ILDTGPDPFP YRPGKPNMQE NSLLDYYKQI
     DDRAEFGELI EPEFVLANFS HAGQIKPVRT FGGTKQLGAI RAFTRTLCKD DLTFVDINEL
     VTLDPVPTRI PQHQFKLQQQ ALEKQAEKNE ALQEKILKSY NQQILGSQTR PVSELKDYIT
     IEPMEQTRDF LNSRMISREM LNGTPMDAII KCSPQKQQPQ FQAMSRGNTP VNIVHHQSAL
     QHVVEESLQD NGGYTLSLRG WFLNHLIRLN PLERSLVYLN LSFNSFEEFP QALFSCKMLK
     VLKLRDNPIS EIPAEIKELS RLKILMLSFC KIEKISKEFC ALPALVYCDL SYNYLSEIRP
     EFGQLKTLKY LNLSGNQLHG FPKQMMKLNL ERIKFKNNFM RVAFWKDFKL EKRDDQIEEE
     THNSDEDELC CDICGAAAGS NSYTVLRPCS EIWGKTKVPF LIKCCGWECA QTANAAGSAT
     ELS
//