ID E4XU70_OIKDI Unreviewed; 1941 AA.
AC E4XU70;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=Myosin motor domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=GSOID_T00004047001 {ECO:0000313|EMBL:CBY13267.1};
OS Oikopleura dioica (Tunicate).
OC Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC Oikopleuridae; Oikopleura.
OX NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY13267.1};
RN [1] {ECO:0000313|EMBL:CBY13267.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21097902; DOI=10.1126/science.1194167;
RA Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA Roest Crollius H., Wincker P., Chourrout D.;
RT "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT pelagic tunicate.";
RL Science 330:1381-1385(2010).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; FN653173; CBY13267.1; -; Genomic_DNA.
DR InParanoid; E4XU70; -.
DR Proteomes; UP000001307; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01377; MYSc_class_II; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 4.
DR Gene3D; 1.20.5.370; -; 3.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF67; MYOSIN-6; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000001307}.
FT DOMAIN 32..83
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 87..791
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 663..685
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1124..1182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1191..1210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1867..1915
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1124..1164
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1875..1896
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 180..187
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1941 AA; 223677 MW; AE072848C5E77186 CRC64;
MSLWDADAAG NAAQWLRLPQ ETMLEIQNRP YTGRNAVWVP NSSTQYCKGE LVGDGKKPGH
KLIKREDGKE KEYHEDHIEF QNPPKYELLE DLANLTYLSE ASVVYNLSER YRRFMIYTYS
GLFCITVNPY KWLTVYDNHV VGIYKGKRKS EMPPHIFAIS DNAYNDMLRE RHNQSMLITG
ESGAGKTVNT KRVIQYFAVV AALGQSAKGN DDGGGTLEDQ IVAANPAMEA FGNAKTTRND
NSSRFGKFIR IHFGMTGKLA SGDIDTYLLE KSRVVFQLPS ERGFHVFYQI CSGGRPDLNE
MTLTTTDPYD FHFCSMGEIK VKSINDVEEL EATDGSFDIL GFEPAEKSGI WQVTAGLMHS
GNMKFKNKQR EEQAEADGTE ASEKAGFMFG ISGADFVKAL CYPRVKVGAD FVTKGQTCPQ
VSYGLGAICK SVFERLFNWI VTTVNRALST DAPRNFFIGI LDIAGFEIFD FNTFEQLCIN
YTNEKLQQFF NHHMFVLEQE EYRKEGIEWS MMDFGMDLAA TLELIERPLG IMSILEEECM
FPKATDMTFK EKLFQTHMGK NDKFGKVVKT KPKDKSIDEP HFEIHHYAGT VGYNVTDWLQ
KNKDPLNTTV VDLFKKSSSK IMQSLWADFA SADETAKKSS GKGGKRQKGG SFQTVSALHR
ESLNRLMTNL RSTQPHFVRC IVPNEIKKPG EMDWNLVLHQ LRCNGVLEGI RICRKGFPSR
VQYDEFTQRY LILAPSVEKG SGEFSDPKKA AQNVLASLAE SGAMDQDKYR LGHTKLFFRA
GAIGDLEDLR DEKISSILTS LQCFFRYKLA AIKFNELNKR RNAIERIQTN IRCFQYLKDW
EWMKIMFKIK PLISQAEEGK KLQELEKNYA ECKTALEKET KRRKELEEAQ VSLVQEKNEL
EQKMNGQLTL LEDAETRCEE LIEQKIDLDA KCRDMQEKLE DEEELNNDLV AKKRKLEDEC
SELKKDIDDL ELTLAKIEKE KHATENKVKN VTEELGSVDE AIVKLEKEKK ALQEAQKQTL
ADLQNEEEKV GTLQKTKGKL ETQVDDLEIT LEAEKKNRMD LERAKRKLEG DIRLTQENVM
DLENDKAGEE EKLKKSEFDF SQMNAKLEDE QALCSQLNKK IKELQSRTEE VEEELESERA
SRGRSEKTRT DLSRELEELA ERLEESASNT QTEVEASKRR DAEMAKIRRE LEETTLNHES
TLSNTRKKQS DQICALSGSV DQFSRQKQKL EKEKSEMKME VDDLQQNVEQ LTKSKLNYEK
QNRNTEDQII EYKQKLEEAD STLNTLMTNK SKNANEINEL RRLIEEKEAS FNQVQRARNS
LTQTNEEIKR QLEEETKFKN AYSHQLQQTK HDIDMLREHY EEEQEGKQEV QRNLAKGQGE
VVFWRNKYET DAIQRTEELE EAKKKLVNRL QDAEEQMEAA QGRCGSLDKT KTRLQGEVED
LSSDLERSNA AAVQLDKKQR NFDKLLAETK QKQEELQVEL EVSQKDARHQ QSELFTLKNA
VEESNDQLES INRENRNLAE EVLECQESLA EGAKTIHDLE KSKRELETLR SEIQSTLEES
ESAIEAEEAK SMRVQVELQQ IKQEIDRKLA EKDEELDNNR RNHTRALEQI QASLDNEMRA
RGEAVRSRKK MESDLNDLEV QCRHIRKQAD DAIKTGKELL NSHKELNINL DEHQRESEDI
KEQSQVAERR VNLMSGEIEE LRGGLEQAER QRKQAENDLM EANERANMLH TQNTAFINQK
RKIENELGTV RNEVEEAITE ARSAEEAAKK ALTTAALLAE DLKKEQDTSH HMERMKKNHE
NSVKDLQMRL DEAEQVALKG GKKQVQKLET KIREIEGELE SEHRRNAEHT KVVRKLERKI
KESNYTNTES KKNLTRVTDQ TDKLQSKVRN FKKQSEEATE SAQMSASRYR KLQHELDEAQ
ERAELAEAAV AKARNRQREQ I
//
