ID E4Y017_OIKDI Unreviewed; 266 AA.
AC E4Y017;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:CBY15229.1};
GN ORFNames=GSOID_T00012125001 {ECO:0000313|EMBL:CBY15229.1};
OS Oikopleura dioica (Tunicate).
OC Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC Oikopleuridae; Oikopleura.
OX NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY15229.1};
RN [1] {ECO:0000313|EMBL:CBY15229.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21097902; DOI=10.1126/science.1194167;
RA Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA Roest Crollius H., Wincker P., Chourrout D.;
RT "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT pelagic tunicate.";
RL Science 330:1381-1385(2010).
CC -!- SIMILARITY: Belongs to the DDAH family.
CC {ECO:0000256|ARBA:ARBA00008532}.
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DR EMBL; FN653449; CBY15229.1; -; Genomic_DNA.
DR AlphaFoldDB; E4Y017; -.
DR InParanoid; E4Y017; -.
DR Proteomes; UP000001307; Unassembled WGS sequence.
DR GO; GO:0016403; F:dimethylargininase activity; IEA:UniProtKB-EC.
DR InterPro; IPR033199; DDAH-like.
DR PANTHER; PTHR12737:SF9; DIMETHYLARGININASE; 1.
DR PANTHER; PTHR12737; DIMETHYLARGININE DIMETHYLAMINOHYDROLASE; 1.
DR Pfam; PF19420; DDAH_eukar; 1.
DR SUPFAM; SSF55909; Pentein; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000001307}.
FT ACT_SITE 163
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-1"
FT ACT_SITE 259
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-1"
FT BINDING 20
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-2"
FT BINDING 63
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-2"
FT BINDING 68..69
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-2"
FT BINDING 88
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-2"
FT BINDING 136
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-2"
FT BINDING 253
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR633199-2"
SQ SEQUENCE 266 AA; 29232 MW; A72837D5BB7D57F3 CRC64;
MEYNTAVCRG IPKSLIEGGL RLENDHSPID EALMRRQHDE YTDALKKCGL KVIELPADES
LPDCVFTEDA AVVFVKKAVL TNQGHPARRA EVNEMRKALE QAGVEIFDMT EEPDSHVDGG
DVLFTGSEIF IGDSKRSNKA GADFLRKSFG IPVHQIKVDE GLHLKSNCSM LGLNKIIISN
DKDGKSMAKE IMEAAQNPYT FVFVSDIKAS NVVSFNKTVF IPAGYPESRK IIEENVGKEI
KLVELGNTEL AKVDGCLTCC SILINA
//
