ID   E4Y108_OIKDI            Unreviewed;       770 AA.
AC   E4Y108;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=Peptidase S1 domain-containing protein {ECO:0000259|PROSITE:PS50240};
GN   ORFNames=GSOID_T00013852001 {ECO:0000313|EMBL:CBY15554.1};
OS   Oikopleura dioica (Tunicate).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC   Oikopleuridae; Oikopleura.
OX   NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY15554.1};
RN   [1] {ECO:0000313|EMBL:CBY15554.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21097902; DOI=10.1126/science.1194167;
RA   Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA   Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA   Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA   Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA   Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA   Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA   Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA   Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA   Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA   Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA   Roest Crollius H., Wincker P., Chourrout D.;
RT   "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT   pelagic tunicate.";
RL   Science 330:1381-1385(2010).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FN653554; CBY15554.1; -; Genomic_DNA.
DR   AlphaFoldDB; E4Y108; -.
DR   MEROPS; S01.078; -.
DR   InParanoid; E4Y108; -.
DR   Proteomes; UP000001307; Unassembled WGS sequence.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd00190; Tryp_SPc; 2.
DR   Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR   InterPro; IPR001314; Peptidase_S1A.
DR   InterPro; IPR001254; Trypsin_dom.
DR   InterPro; IPR018114; TRYPSIN_HIS.
DR   InterPro; IPR033116; TRYPSIN_SER.
DR   PANTHER; PTHR24252; ACROSIN-RELATED; 1.
DR   PANTHER; PTHR24252:SF7; HYALIN; 1.
DR   Pfam; PF00089; Trypsin; 2.
DR   PRINTS; PR00722; CHYMOTRYPSIN.
DR   SMART; SM00020; Tryp_SPc; 2.
DR   SUPFAM; SSF50494; Trypsin-like serine proteases; 2.
DR   PROSITE; PS50240; TRYPSIN_DOM; 2.
DR   PROSITE; PS00134; TRYPSIN_HIS; 2.
DR   PROSITE; PS00135; TRYPSIN_SER; 1.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Hydrolase {ECO:0000256|RuleBase:RU363034};
KW   Protease {ECO:0000256|RuleBase:RU363034};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001307};
KW   Serine protease {ECO:0000256|RuleBase:RU363034}.
FT   DOMAIN          51..286
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000259|PROSITE:PS50240"
FT   DOMAIN          322..558
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000259|PROSITE:PS50240"
SQ   SEQUENCE   770 AA;  84253 MW;  00280A87112D2B9A CRC64;
     MRLFKTFNAI LLHDAAARMS AAESSEDTLR GLLDLGLTCQ GSQDTRSAHR IVGGTEVQPA
     TWPWIVRFPS IGCAGSIIGP RTVVTAAHCC FTDSVSIFDF VAGKHSRIDN FAQDPFTRRY
     RASAIRKHRS YTSSTFESDI CLVFADEDIQ FNDAVQPVCL PSAPVEIRQE DCYVAGWGRT
     SWNGFQASKL LEIPAIIYDV ETECNPNYRE NGNTPLIDEV MICAGNMAGG IDACQGDSGG
     PLVCLENGVP VMHGVVSWGV KCAEADLPGV YTRTSAMLDW IEEQQIEVLG APQTNDPPPH
     DQDKIESGLT GLSCLDSEEN RIMGGQQATY GSWPFIGRLE KGCAATIIGH NVALTAAHCC
     QDQGLWNYDL NAGVHHSFNT NMDGWKDHHW ATKVVAHPDY DLVTKDNDIC LIFYQQSFDW
     SPGVQPACLP SGPSQINRKC HVAGWGSKSH TSTATSSVLM EAQINIYNST EECEPVFSSS
     DEASENGEVT DNMICAGWKE GGVDACSGDT GGPLVCVEDG KPVVTGIVSW GFKCGIPNFP
     SMYTDVSRYT DWIQKEISES TSCDRDDLAN ISGVQGDGEW VCDDSDECTW TCEDGHATGA
     VTRCSNKQWT ALTSAMRKTA RCDRCNLSVD SVKTSSSAPA AQLDCSFSRN TKSCKLKCLS
     EDGVFGETNT EVWCDRSKAK NRFSAVRGKS GNLSCVPLCD RTEFEAKVMG KWADFDMSDF
     KEMQSSHPIF WKMKCKNSSK VSKKTFARCQ VTRTGKEKIL IKGDYNDPKC
//