ID   E4Y2R4_OIKDI            Unreviewed;       404 AA.
AC   E4Y2R4;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   22-FEB-2023, entry version 31.
DE   RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN   ORFNames=GSOID_T00016470001 {ECO:0000313|EMBL:CBY16148.1};
OS   Oikopleura dioica (Tunicate).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC   Oikopleuridae; Oikopleura.
OX   NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY16148.1};
RN   [1] {ECO:0000313|EMBL:CBY16148.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21097902; DOI=10.1126/science.1194167;
RA   Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA   Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA   Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA   Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA   Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA   Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA   Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA   Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA   Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA   Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA   Roest Crollius H., Wincker P., Chourrout D.;
RT   "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT   pelagic tunicate.";
RL   Science 330:1381-1385(2010).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FN653919; CBY16148.1; -; Genomic_DNA.
DR   AlphaFoldDB; E4Y2R4; -.
DR   InParanoid; E4Y2R4; -.
DR   Proteomes; UP000001307; Unassembled WGS sequence.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001307}.
FT   DOMAIN          117..211
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          383..404
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          327..354
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   404 AA;  46318 MW;  12F27952935A2A30 CRC64;
     MLSSFSKSFR NSFRKIRKND DERRDDKRTQ SMNINRSYST DAHIYSTSFM DCQESQNNSI
     NPERSLGEFK KREHPLSRVK STFSLGRMNK TRTSASSFSA MADVSQLKRK VDILEFDNNV
     KGYLRVKFGD SGWKRHYAIL HQDTIALYVE KYDVNPVMES TLTGNIVAPG ETYTRKKYAF
     CVKGAHTHLL FSCKDKEDLF RWMNAVSLAS IGYDVDEGKT IGIKKNRYNS CSIRINRGRK
     VFKQYASVGS DGQSISSKED DLCDISLIQM KISREETLSR KNAQMQKSKS TASDIMRLVD
     VVDITSGLTR KQTMKRRAEK LSSDPKLNEV LHKKLQLERE LRSMNTDLEI INKLFEVPLT
     NEKIDDFLQK HGDIIPNLKE TTSLEDSLSS PQSDISSNTV DSLW
//