ID   E4YF15_OIKDI            Unreviewed;       588 AA.
AC   E4YF15;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=SET domain-containing protein {ECO:0000259|PROSITE:PS50280};
GN   ORFNames=GSOID_T00024098001 {ECO:0000313|EMBL:CBY34102.1};
OS   Oikopleura dioica (Tunicate).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC   Oikopleuridae; Oikopleura.
OX   NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY34102.1};
RN   [1] {ECO:0000313|EMBL:CBY34102.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21097902; DOI=10.1126/science.1194167;
RA   Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA   Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA   Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA   Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA   Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA   Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA   Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA   Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA   Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA   Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA   Roest Crollius H., Wincker P., Chourrout D.;
RT   "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT   pelagic tunicate.";
RL   Science 330:1381-1385(2010).
CC   -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
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DR   EMBL; FN654475; CBY34102.1; -; Genomic_DNA.
DR   AlphaFoldDB; E4YF15; -.
DR   Proteomes; UP000011014; Unassembled WGS sequence.
DR   CDD; cd00024; CD_CSD; 1.
DR   Gene3D; 2.170.270.10; SET domain; 1.
DR   InterPro; IPR016197; Chromo-like_dom_sf.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   PANTHER; PTHR46223:SF3; HISTONE H3 (LYS9) METHYLTRANSFERASE-RELATED; 1.
DR   PANTHER; PTHR46223; HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H; 1.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00317; SET; 1.
DR   SUPFAM; SSF54160; Chromo domain-like; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          402..528
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   588 AA;  68790 MW;  57F58553474927CD CRC64;
     MKIEPSVSKV TDKPTTRRSR RLLAPISAQL PVTSQKPVSR TRASSDILFE ETNVEEQIFK
     IKPECVNELK STKVRFPKMM TMAFLREIAD SFKNSVNNVE SRCKSLKKRY TWLDTEDEKD
     WFYKSCSEYP TAQMLPEASP SEILRVDYFR KTFGWEKRHA NTCARKAEYI LDFKRKSRND
     LYKVKWCGLP EYAATWVRPV DIIAFRYEFA RRVTEFWEAV VKLVPHKEMP IVRRSNCSIP
     AEYISKICSN YQKIKRESMI EICAENPLKS ALLIENEYDV CASPFNFEFI SENAFCGAKE
     QLKAYEDEKA TQKQVAEALG FCCKQECGEC SANFYKEYAL ASHKATYSKH KHYKYDEERD
     YWKVCHPAHF LIFECTDDCI CKKEGRCKLD MLTKLRDNHS SNKFLVSRTG DDRGWGLTAM
     QAFKQGEPVI EYVGELMTEE NFRQNETEIW NKNLMYSMDL TQNDKNLPAY TVDSSRKGNH
     SRLINHSCEP NLVTYKIIKE DRNINRPHPV LFAAKDIAIG EELSFNYKLT IINQNENSKH
     DDNSDSEHEF DVVENGRAFI CRCGSKKCID KKKNLKRKHD RKRSNKMR
//