ID E4YGB0_OIKDI Unreviewed; 520 AA.
AC E4YGB0;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=Synapsin ATP-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=GSOID_T00024560001 {ECO:0000313|EMBL:CBY34534.1};
OS Oikopleura dioica (Tunicate).
OC Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC Oikopleuridae; Oikopleura.
OX NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY34534.1};
RN [1] {ECO:0000313|EMBL:CBY34534.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21097902; DOI=10.1126/science.1194167;
RA Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA Roest Crollius H., Wincker P., Chourrout D.;
RT "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT pelagic tunicate.";
RL Science 330:1381-1385(2010).
CC -!- SIMILARITY: Belongs to the synapsin family.
CC {ECO:0000256|ARBA:ARBA00008243}.
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DR EMBL; FN654518; CBY34534.1; -; Genomic_DNA.
DR AlphaFoldDB; E4YGB0; -.
DR Proteomes; UP000011014; Unassembled WGS sequence.
DR GO; GO:0008021; C:synaptic vesicle; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0007269; P:neurotransmitter secretion; IEA:InterPro.
DR Gene3D; 3.40.50.20; -; 1.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR016185; PreATP-grasp_dom_sf.
DR InterPro; IPR001359; Synapsin.
DR InterPro; IPR020898; Synapsin_ATP-bd_dom.
DR InterPro; IPR020897; Synapsin_pre-ATP-grasp_dom.
DR PANTHER; PTHR10841; SYNAPSIN; 1.
DR PANTHER; PTHR10841:SF17; SYNAPSIN; 1.
DR Pfam; PF02078; Synapsin; 1.
DR Pfam; PF02750; Synapsin_C; 1.
DR PRINTS; PR01368; SYNAPSIN.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF52440; PreATP-grasp domain; 1.
PE 3: Inferred from homology;
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Synapse {ECO:0000256|ARBA:ARBA00023018}.
FT DOMAIN 126..231
FT /note="Synapsin pre-ATP-grasp"
FT /evidence="ECO:0000259|Pfam:PF02078"
FT DOMAIN 233..440
FT /note="Synapsin ATP-binding"
FT /evidence="ECO:0000259|Pfam:PF02750"
FT REGION 1..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 459..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 520 AA; 57892 MW; 28D23DFF2A94010C CRC64;
MEYIRRRLSE TNLGLTGADN QQPSTMDAAP SNGYMVPTAT STTTTNSAAS TRRTSESGTT
RQGEMMQSTD QPQKSKAGFF SGIMNNPAPG TAQPGPKLAN AASTASNFLS NMASAVNVSN
IKTDSTSKCL LVIENRSTDW GKAFANKTVQ GMRFRVEQHT FDDLTIIATN EGMVQVWVGS
FPILKKACSR KLRDDNKEIR FRPDFILIRQ QPVSKQHRTV LLGLKLGGIP SINSLHSIYN
MFDPPWVFAQ LARIRMRFGP GLSIFTQTSS LHYYQEFPVT TKTFMPTANC LRRFRDFPAI
VSSSNRSDAR LRVRNRDQVE DIIPILQQID DYIMVEPLVK AAYELHVTRI GGIYSVYVQT
SPQEGNPVVE RVEITPRYKL WIDAVCELFG GLDIAGIRAI HTADGKDIIV NVESSWLNLP
NAAAQNDEAL IVDVIVKKME LASRPQSIAK NVGQTIVNPH HKKMASEPCT PERPTPKVRQ
SLPSSPEVTR KNTFAANPLD GENAEKIRDM RNSFMSYFNK
//
