ID   E4Z689_OIKDI            Unreviewed;       311 AA.
AC   E4Z689;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=tRNA N(3)-methylcytidine methyltransferase {ECO:0000256|PIRNR:PIRNR037755};
DE            EC=2.1.1.- {ECO:0000256|PIRNR:PIRNR037755};
GN   ORFNames=GSOID_T00027796001 {ECO:0000313|EMBL:CBY43217.1};
OS   Oikopleura dioica (Tunicate).
OC   Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Copelata;
OC   Oikopleuridae; Oikopleura.
OX   NCBI_TaxID=34765 {ECO:0000313|EMBL:CBY43217.1};
RN   [1] {ECO:0000313|EMBL:CBY43217.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21097902; DOI=10.1126/science.1194167;
RA   Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C.,
RA   Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C.,
RA   Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., Cross I.,
RA   Yadetie F., Muffato M., Louis A., Butcher S., Tsagkogeorga G., Konrad A.,
RA   Singh S., Jensen M.F., Cong E.H., Eikeseth-Otteraa H., Noel B.,
RA   Anthouard V., Porcel B.M., Kachouri-Lafond R., Nishino A., Ugolini M.,
RA   Chourrout P., Nishida H., Aasland R., Huzurbazar S., Westhof E., Delsuc F.,
RA   Lehrach H., Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F.,
RA   Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., Du Pasquier L.,
RA   Boudinot P., Liberles D.A., Volff J.N., Philippe H., Lenhard B.,
RA   Roest Crollius H., Wincker P., Chourrout D.;
RT   "Plasticity of animal genome architecture unmasked by rapid evolution of a
RT   pelagic tunicate.";
RL   Science 330:1381-1385(2010).
CC   -!- FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase.
CC       {ECO:0000256|PIRNR:PIRNR037755}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily. METL family.
CC       {ECO:0000256|PIRNR:PIRNR037755}.
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DR   EMBL; FN657960; CBY43217.1; -; Genomic_DNA.
DR   AlphaFoldDB; E4Z689; -.
DR   Proteomes; UP000011014; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR026113; METTL2/6/8-like.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR22809:SF11; METHYLTRANSFERASE-LIKE PROTEIN; 1.
DR   PANTHER; PTHR22809; METHYLTRANSFERASE-RELATED; 1.
DR   Pfam; PF13489; Methyltransf_23; 1.
DR   PIRSF; PIRSF037755; Mettl2_prd; 2.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Methyltransferase {ECO:0000256|PIRNR:PIRNR037755};
KW   Transferase {ECO:0000256|PIRNR:PIRNR037755}.
FT   COILED          34..64
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   311 AA;  36296 MW;  C27526A43F83144B CRC64;
     MSEEGKRPQF GNRKITEESE IFKHNAWDQV EWGAEQEEDA LEQIRKQKEK SENVEERMKL
     AGETASDNWN CFYEKHENKF FKDRSWLFTE FERLNPKNSP ELTVLELGCG NGSNVVPLLE
     ATTSHQNYKV FEIFKSSRTN YISFSPTPFS GCDFAPKSVE ICKELVQKYG DRAHIFRHDL
     ASEEPIQIPD KVDVVICTFV LSALPFDRME SAIAKMTECL KAGGDIFFRD YGRYDMSQLR
     FKPTRVAGEN TYTRGDGTLV YFFTEDDVAK LFESTGLRRE QLLTDRRLQI NRAKRLKMYR
     VWEQAVYRKS S
//