ID E4ZQB1_LEPMJ Unreviewed; 900 AA.
AC E4ZQB1;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Similar to subtilisin-like serine protease {ECO:0000313|EMBL:CBX93586.1};
GN ORFNames=LEMA_P032600.1 {ECO:0000313|EMBL:CBX93586.1};
OS Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)
OS (Blackleg fungus) (Phoma lingam).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Leptosphaeriaceae;
OC Plenodomus; Plenodomus lingam/Leptosphaeria maculans species complex.
OX NCBI_TaxID=985895 {ECO:0000313|Proteomes:UP000002668};
RN [1] {ECO:0000313|Proteomes:UP000002668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8
RC {ECO:0000313|Proteomes:UP000002668};
RX PubMed=21326234; DOI=10.1038/ncomms1189;
RA Rouxel T., Grandaubert J., Hane J.K., Hoede C., van de Wouw A.P.,
RA Couloux A., Dominguez V., Anthouard V., Bally P., Bourras S.,
RA Cozijnsen A.J., Ciuffetti L.M., Degrave A., Dilmaghani A., Duret L.,
RA Fudal I., Goodwin S.B., Gout L., Glaser N., Linglin J., Kema G.H.J.,
RA Lapalu N., Lawrence C.B., May K., Meyer M., Ollivier B., Poulain J.,
RA Schoch C.L., Simon A., Spatafora J.W., Stachowiak A., Turgeon B.G.,
RA Tyler B.M., Vincent D., Weissenbach J., Amselem J., Quesneville H.,
RA Oliver R.P., Wincker P., Balesdent M.-H., Howlett B.J.;
RT "Effector diversification within compartments of the Leptosphaeria maculans
RT genome affected by Repeat-Induced Point mutations.";
RL Nat. Commun. 2:202-202(2011).
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; FP929116; CBX93586.1; -; Genomic_DNA.
DR RefSeq; XP_003837026.1; XM_003836978.1.
DR AlphaFoldDB; E4ZQB1; -.
DR STRING; 985895.E4ZQB1; -.
DR EnsemblFungi; CBX93586; CBX93586; LEMA_P032600.1.
DR GeneID; 13285337; -.
DR eggNOG; KOG4266; Eukaryota.
DR HOGENOM; CLU_003559_3_1_1; -.
DR InParanoid; E4ZQB1; -.
DR OMA; FNHPALG; -.
DR OrthoDB; 662485at2759; -.
DR Proteomes; UP000002668; Genome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd07489; Peptidases_S8_5; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 2.
DR InterPro; IPR010435; Fn3_5.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034187; Peptidases_S8_5.
DR PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF06280; fn3_5; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000002668};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..900
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003193093"
FT DOMAIN 172..598
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 643..747
FT /note="Fn3-like"
FT /evidence="ECO:0000259|Pfam:PF06280"
FT ACT_SITE 181
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 232
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 564
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 900 AA; 96637 MW; F794289CF84060A7 CRC64;
MGKFSRAIVA LILGAQVAVS TPVHPRLHPN AIVQRAVNNT TPTGGILPGA YIVEFANDNE
TPETFYASLA ASGVIVEHRM DLSFRLFKGV SFQLKSSGFN SSGGDFLRQM KAQPQVENIW
PTRITTRPTV GVNSVAAPDQ QTRIKRQTTA NRTFSPHVMT QVDRLHAEGV TGKGFRVAVI
DGGIDYTHPA LGGCFGPGCL VEAGYDFVGD NYTVGLSEPQ PDDDPLDTCE GHGTHVSGTI
AAQLEGNEYG FTGSAPGAKL GAYRMWGCSA ASTNDIELMA FARAVEDGAD IISYSNGDTS
SWAQDVRAVI ISRIVDSGIP VVVSEGNSGF QGLFFASTPA TGLSITGVGA VSNSLFPALL
DQGSYTTSAN ATTNGTNEFS FLMGVPKFTA HTTLQLWSAA DVDDACKPLP DDTPDLSQRI
VLLEFKDARA TQCYPQDQGA NIAAKGGRFM AYYEHSNLTM RDETYVYANG IEGVVRVVPY
IAERWLSLLS QGTTVSVTIP ANGTKKQLEE LENNQSGGYI SGDLSSWGPT WELSMTPELV
SPGENILSTW PTAMGSYRVL TGTSMATPLV AGVYALLGEV YGKLEPVRLR RILTHTSKPL
AWHDGRTAHP DMLAPVTQQG GGIVQAWKAA RTTLEIDVDS LMLNDTAHFV GTHTFSITNT
GSTDEILELT HRKAVTMYTM DARFSPLTPG SFPNAIAESW ATVSFSADRI TVPAGQSANV
TVEIIPPAGL NATLLPVYSG YIALSDKLVL PYLGVAGNMR DIPVLGPENA YLATGFAQVP
ANASYTIPRP DPQNPPAVDR GDMINSPNMY IKPWVGTKLL RVEVLQGNTI LGALAGFPQM
FLPRSDELRA FFNGLLADGR VLDEGSYKMR VMALRVFGDE EREEDWDVVE SIPFAIKYAA
//
