ID E5A8X3_LEPMJ Unreviewed; 564 AA.
AC E5A8X3;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Similar to sugar transporter {ECO:0000313|EMBL:CBY00068.1};
GN ORFNames=LEMA_P076570.1 {ECO:0000313|EMBL:CBY00068.1};
OS Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)
OS (Blackleg fungus) (Phoma lingam).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Leptosphaeriaceae;
OC Plenodomus; Plenodomus lingam/Leptosphaeria maculans species complex.
OX NCBI_TaxID=985895 {ECO:0000313|Proteomes:UP000002668};
RN [1] {ECO:0000313|Proteomes:UP000002668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8
RC {ECO:0000313|Proteomes:UP000002668};
RX PubMed=21326234; DOI=10.1038/ncomms1189;
RA Rouxel T., Grandaubert J., Hane J.K., Hoede C., van de Wouw A.P.,
RA Couloux A., Dominguez V., Anthouard V., Bally P., Bourras S.,
RA Cozijnsen A.J., Ciuffetti L.M., Degrave A., Dilmaghani A., Duret L.,
RA Fudal I., Goodwin S.B., Gout L., Glaser N., Linglin J., Kema G.H.J.,
RA Lapalu N., Lawrence C.B., May K., Meyer M., Ollivier B., Poulain J.,
RA Schoch C.L., Simon A., Spatafora J.W., Stachowiak A., Turgeon B.G.,
RA Tyler B.M., Vincent D., Weissenbach J., Amselem J., Quesneville H.,
RA Oliver R.P., Wincker P., Balesdent M.-H., Howlett B.J.;
RT "Effector diversification within compartments of the Leptosphaeria maculans
RT genome affected by Repeat-Induced Point mutations.";
RL Nat. Commun. 2:202-202(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000256|ARBA:ARBA00008335}.
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DR EMBL; FP929137; CBY00068.1; -; Genomic_DNA.
DR RefSeq; XP_003843547.1; XM_003843499.1.
DR AlphaFoldDB; E5A8X3; -.
DR EnsemblFungi; CBY00068; CBY00068; LEMA_P076570.1.
DR GeneID; 13289345; -.
DR eggNOG; KOG0253; Eukaryota.
DR HOGENOM; CLU_001265_52_2_1; -.
DR InParanoid; E5A8X3; -.
DR OMA; GAFIWLP; -.
DR OrthoDB; 2615066at2759; -.
DR Proteomes; UP000002668; Genome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR CDD; cd17316; MFS_SV2_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23511:SF12; MAJOR FACILITATOR-TYPE TRANSPORTER HXNZ-RELATED; 1.
DR PANTHER; PTHR23511; SYNAPTIC VESICLE GLYCOPROTEIN 2; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002668};
KW Sugar transport {ECO:0000313|EMBL:CBY00068.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000313|EMBL:CBY00068.1}.
FT TRANSMEM 103..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 417..438
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 450..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 474..494
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 514..531
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 537..556
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 103..559
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 564 AA; 61575 MW; EB10D0396587B09C CRC64;
MPRDSQILTP YLHVRLNART ARCFGDHATY NLDCTQEVPL NAIMFTSKTE GDNKEMTQEV
PSVLDAPVSV LEDGSLDPVY EGKAKVLNKA IQDIGMGKYQ WQLFIVIGFG WSMDNLWPIV
TSLIFTPIRN EFNPTRAPFL TLAQNIGLLF GAVFWGFGCD IFGRRWAFNL TIGITAIFGM
AAAGSPNFAA IGIFAALWSV GVGGNLPVDS AIFLEFLPGT HQYLLTILSI FWSLAQVFAT
LVAWPLLGNM SCQQIDTECT KSKNMGWRYF MIVMGGVALI MFFFRFVLFT LYESPKFLMG
KGKDEEAVRV VHEVARRNGR TTTLSLEDLK VCESLALPGS STSQQVTATA TVKRKLQKLN
TSHVKALFAT KKLAFSTSII TVVWAFIGLG FPLYNAFLPF IQATRGASFG ESSTYLTYRN
TLIIAVLGVP GCLLGGLLVE TPRVGRKGTL AGSTILTGVF LFGSTTALNS NSLLGWNCAY
NFMSNIMYAV LYAYTPETFV TKDRGTGNAI TASANRIFGI MAPIVAMFAN LETSAPVYVS
GALFIAAGLL VLILPFESRG KASM
//
