ID E5A958_LEPMJ Unreviewed; 887 AA.
AC E5A958;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Similar to periodic tryptophan protein 2 {ECO:0000313|EMBL:CBY00199.1};
GN ORFNames=LEMA_P013290.1 {ECO:0000313|EMBL:CBY00199.1};
OS Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)
OS (Blackleg fungus) (Phoma lingam).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Leptosphaeriaceae;
OC Plenodomus; Plenodomus lingam/Leptosphaeria maculans species complex.
OX NCBI_TaxID=985895 {ECO:0000313|Proteomes:UP000002668};
RN [1] {ECO:0000313|Proteomes:UP000002668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8
RC {ECO:0000313|Proteomes:UP000002668};
RX PubMed=21326234; DOI=10.1038/ncomms1189;
RA Rouxel T., Grandaubert J., Hane J.K., Hoede C., van de Wouw A.P.,
RA Couloux A., Dominguez V., Anthouard V., Bally P., Bourras S.,
RA Cozijnsen A.J., Ciuffetti L.M., Degrave A., Dilmaghani A., Duret L.,
RA Fudal I., Goodwin S.B., Gout L., Glaser N., Linglin J., Kema G.H.J.,
RA Lapalu N., Lawrence C.B., May K., Meyer M., Ollivier B., Poulain J.,
RA Schoch C.L., Simon A., Spatafora J.W., Stachowiak A., Turgeon B.G.,
RA Tyler B.M., Vincent D., Weissenbach J., Amselem J., Quesneville H.,
RA Oliver R.P., Wincker P., Balesdent M.-H., Howlett B.J.;
RT "Effector diversification within compartments of the Leptosphaeria maculans
RT genome affected by Repeat-Induced Point mutations.";
RL Nat. Commun. 2:202-202(2011).
CC -!- SIMILARITY: Belongs to the WD repeat PWP2 family.
CC {ECO:0000256|ARBA:ARBA00010226}.
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DR EMBL; FP929138; CBY00199.1; -; Genomic_DNA.
DR RefSeq; XP_003843678.1; XM_003843630.1.
DR AlphaFoldDB; E5A958; -.
DR STRING; 985895.E5A958; -.
DR EnsemblFungi; CBY00199; CBY00199; LEMA_P013290.1.
DR GeneID; 13290327; -.
DR eggNOG; KOG0291; Eukaryota.
DR HOGENOM; CLU_010458_0_0_1; -.
DR InParanoid; E5A958; -.
DR OMA; VYEWQSE; -.
DR OrthoDB; 23263at2759; -.
DR Proteomes; UP000002668; Genome.
DR GO; GO:0005737; C:cytoplasm; IEA:EnsemblFungi.
DR GO; GO:0034388; C:Pwp2p-containing subcomplex of 90S preribosome; IEA:EnsemblFungi.
DR GO; GO:0032040; C:small-subunit processome; IEA:EnsemblFungi.
DR GO; GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR GO; GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR GO; GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR GO; GO:0030010; P:establishment of cell polarity; IEA:EnsemblFungi.
DR GO; GO:0000920; P:septum digestion after cytokinesis; IEA:EnsemblFungi.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 4.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR027145; PWP2.
DR InterPro; IPR011044; Quino_amine_DH_bsu.
DR InterPro; IPR007148; SSU_processome_Utp12.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19858:SF0; PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG-RELATED; 1.
DR PANTHER; PTHR19858; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF04003; Utp12; 1.
DR Pfam; PF00400; WD40; 5.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 13.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR SUPFAM; SSF50969; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 3.
DR PROSITE; PS50082; WD_REPEATS_2; 5.
DR PROSITE; PS50294; WD_REPEATS_REGION; 5.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002668};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 146..187
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 190..222
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 336..377
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 378..419
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 464..505
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 739..844
FT /note="Small-subunit processome Utp12"
FT /evidence="ECO:0000259|Pfam:PF04003"
FT REGION 637..667
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 807..834
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 887 AA; 98627 MW; 0DF4E1A4339383B9 CRC64;
MKTDFQFSNL LGTVYSRGNL LFTSDGTCLL SPVGNRVTVF DLFNSKSYTL PFAHRRNIAR
LALNPQGNLL LSVDQDGRAI LTNLARRIVL YHFSLRAEVT ALSFAPSGRH FAVGLGRQIE
VWHTPSTPDV TQGELEFAPF VRHRIYTGHY DAVQGLEWSA DSRFFLSASK DMTARIWSVS
QDESLAQTTL SGHRQAIVGA WFSKDQETIY TVSKDGALFI WKYMLRYDAP DDADENDDQN
LQWGIAQRHF FMQNNAHVTC AQFHADSNLL VTGFSHGLFF VHELPSFAQI QSLGISQNDI
DYIAINKTGE WLAFGASNLG QLLVWEWQSE SYVLKQQSHF DSMNTIAYSP EGQRIITAAD
DGKVKVWDVN SGFCIVTFTE HIGGVTACEF AKRGNVLFTA SLDGSIRAWD LIRYRNFRTF
TAPSRLSFSS LAVDPSGEVV CAGSIDSFDI HIWSVQTGQL LDRLAGHEGP VSSLAFSPDA
GTLVSGSWDK TVRIWNIFAR TQTSEPLQLM ADVLSVAFRP DSKQIAVTTL DGQLTFWSVS
EAAQQNGVDA RRDVSGGRKM SDRRTAANVA GTKAFTSVRY SADGTCVLAG GNSKYICLYD
AQSGVLLKKF TVSTNLSLDG TQEFLNSKLL TAAGPQGLID DQGEASDLED RRDATLPGAQ
RGTGARRTRP EIRVPAVAFS PTGRAFCAAS TEGLLIYSLD NTFQFDPFDL DISVTPSTTL
ETLARKEYLK ALVMAFRLNE RNLIRRVYEA IPVADVPLVV QDIPTMYLGR LLRFVALQAD
ESPHLEFNLV WIESLLNKHG RWMKENKGGL EAELRSVEKA VRRIQAELAR LADENIYRIE
YLLSQPVETK ETTLQLDFGV EAIEKIDRDG IIDGNDDREE GDWLGFD
//
