ID E5AA18_LEPMJ Unreviewed; 1294 AA.
AC E5AA18;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Similar to sensor histidine kinase/response regulator {ECO:0000313|EMBL:CBY00509.1};
GN ORFNames=LEMA_P016390.1 {ECO:0000313|EMBL:CBY00509.1};
OS Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)
OS (Blackleg fungus) (Phoma lingam).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Leptosphaeriaceae;
OC Plenodomus; Plenodomus lingam/Leptosphaeria maculans species complex.
OX NCBI_TaxID=985895 {ECO:0000313|Proteomes:UP000002668};
RN [1] {ECO:0000313|Proteomes:UP000002668}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8
RC {ECO:0000313|Proteomes:UP000002668};
RX PubMed=21326234; DOI=10.1038/ncomms1189;
RA Rouxel T., Grandaubert J., Hane J.K., Hoede C., van de Wouw A.P.,
RA Couloux A., Dominguez V., Anthouard V., Bally P., Bourras S.,
RA Cozijnsen A.J., Ciuffetti L.M., Degrave A., Dilmaghani A., Duret L.,
RA Fudal I., Goodwin S.B., Gout L., Glaser N., Linglin J., Kema G.H.J.,
RA Lapalu N., Lawrence C.B., May K., Meyer M., Ollivier B., Poulain J.,
RA Schoch C.L., Simon A., Spatafora J.W., Stachowiak A., Turgeon B.G.,
RA Tyler B.M., Vincent D., Weissenbach J., Amselem J., Quesneville H.,
RA Oliver R.P., Wincker P., Balesdent M.-H., Howlett B.J.;
RT "Effector diversification within compartments of the Leptosphaeria maculans
RT genome affected by Repeat-Induced Point mutations.";
RL Nat. Commun. 2:202-202(2011).
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DR EMBL; FP929138; CBY00509.1; -; Genomic_DNA.
DR RefSeq; XP_003843988.1; XM_003843940.1.
DR STRING; 985895.E5AA18; -.
DR EnsemblFungi; CBY00509; CBY00509; LEMA_P016390.1.
DR GeneID; 13293191; -.
DR eggNOG; KOG0519; Eukaryota.
DR HOGENOM; CLU_002763_0_0_1; -.
DR InParanoid; E5AA18; -.
DR OMA; FDRHTQY; -.
DR OrthoDB; 12386at2759; -.
DR Proteomes; UP000002668; Genome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43047:SF80; HISTIDINE KINASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:CBY00509.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000002668};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 598..863
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1098..1228
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT REGION 44..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 325..377
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 1158
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1294 AA; 142405 MW; A7EC1502FC315B11 CRC64;
MADSLDVARS YAVARRRHKM EQTDSAKIRE QQFYLYYPQH SKSEDLLSRH PSPSPVLHAA
TPPGTPPQTQ TTADYVPRPS EDKALTAFAQ LGALRLNARR CLISFFDRKD CFLLAEGTKT
LSLDTGEAEF AEDRLCFGSV VFPKEQSLCY YTVNLAPKFT NLPLDDPSDL PSLVVNDLAR
DDRFKDLPFV KGPPKSRFYA GVPIRSPSGH SIGTYCVLDD QPRDGLTPHQ LAFLKSMAGT
VMRHLEMTRA TEDQRRGKIM VKSLGSFAEG KSGLENWWQD PWDLAEQSVT AVIPDTINLP
MRQQPFALST AALEPIVLDK IQSAGSSVPS TKNSTVTSPA SVQPPSTATP CSITLPENPR
PLVPTTTSST SANMPTDNIA PEVRATFTRA ANMIVDATEA EGVSFFDAKI STFGGLVDDD
FDPDILPEPD KPCVLLGSAI SKTARESDSQ SANDVAMSES VLKHLLRLYP HGHIFNLDDD
MAMSAFNSPS AGGGDLELSD GFPFTTAQKS ESMRSMDDEA YLRTVFPKAR SLVLYPLWDP
HRDRWFASAV IWSSDPKRVF TSEQELSYLA AFSNSVMAEV ARLDTKLADA AKADFISSIS
HELRSPLHGI LGMTDLLKDS YIDNQQVSHV ATIETCGKTL LETINHVLDF AKINNLTRGA
SKRQKKRTQN ARHMISPGQP HTNDIMTLIN DVDMGILTED VVESVFAGYT YAKTSAQTYE
LSTPTSNKPK LSVVLDINYS GNYVFRTQPG AWRRVIMNLF GNSLKYTPSG FVKVKLEVKR
KPGALEDRCE FRFSVTDSGI GMSEDYINNR LFHSFAQENP LSQGTGLGLS IVKQIVESLG
GEVEVRSEKG RGTKFMVKCP LKESSMSPSF CPTGSEQDKK RQLQAIAKRT KGLKVAFRGF
NTEEDQYVEG LKTKSASKLS LKALDSLCTD WFGMFKCEEG DKATKPDLII ATEACAKILR
SHQNQKPKDA SEAPPVIVVC PGAAAAQSTT AITVPGIVFE CISQPVGPHK LAKALGSCLD
RHTDRQDELK SGTGPPAPKI VELDLKENAD RHRTDQFTYL RDGSRPNLSS INSAPEIRSV
GHCPVKKSIY SAPTRALNCL CVDDNPINLR LLRTFVDKLG HRHVLAINGL KALEHYKAAH
EPPLSEDESN RVDVILMDIN MPEMDGLEAT RQIRAHEIRN NLPKVTIIAL TGVADTDIQQ
EANSSGVNLF LIKPVRLGDL EVILKGVVTG QDKADLEFEQ EKEKQKALNA ARLRATSDGN
EKSRLVSVGV RAISENDPVQ KTVRNQEIKR LSMG
//
