ID   E5CFU8_9BACE            Unreviewed;       303 AA.
AC   E5CFU8;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   24-JAN-2024, entry version 46.
DE   SubName: Full=dTDP-4-dehydrorhamnose reductase {ECO:0000313|EMBL:EFS33621.1};
GN   ORFNames=BSGG_4321 {ECO:0000313|EMBL:EFS33621.1};
OS   Bacteroides sp. D2.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=556259 {ECO:0000313|EMBL:EFS33621.1, ECO:0000313|Proteomes:UP000003135};
RN   [1] {ECO:0000313|EMBL:EFS33621.1, ECO:0000313|Proteomes:UP000003135}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=D2 {ECO:0000313|EMBL:EFS33621.1,
RC   ECO:0000313|Proteomes:UP000003135};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Allen-Vercoe E., Strauss J.,
RA   Sibley C., White A., Young S.K., Zeng Q., Gargeya S., Fitzgerald M.,
RA   Haas B., Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA   Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Goldberg J.,
RA   Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA   MacDonald P.J.P., Montmayeur A., Murphy C., Neiman D., Pearson M.,
RA   Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA   Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Bacteroides sp. D2.";
RL   Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFS33621.1}.
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DR   EMBL; ACGA02000014; EFS33621.1; -; Genomic_DNA.
DR   RefSeq; WP_008998428.1; NZ_JH636018.1.
DR   AlphaFoldDB; E5CFU8; -.
DR   HOGENOM; CLU_045518_2_1_10; -.
DR   OrthoDB; 9803892at2; -.
DR   UniPathway; UPA00124; -.
DR   Proteomes; UP000003135; Unassembled WGS sequence.
DR   GO; GO:0008831; F:dTDP-4-dehydrorhamnose reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019305; P:dTDP-rhamnose biosynthetic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd05254; dTDP_HR_like_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR029903; RmlD-like-bd.
DR   PANTHER; PTHR43242; NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN; 1.
DR   PANTHER; PTHR43242:SF1; NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN; 1.
DR   Pfam; PF04321; RmlD_sub_bind; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
FT   DOMAIN          3..298
FT                   /note="RmlD-like substrate binding"
FT                   /evidence="ECO:0000259|Pfam:PF04321"
SQ   SEQUENCE   303 AA;  34170 MW;  45D378F7D5207A2B CRC64;
     MKKILIIGAN GFTGRQILND LSACKQYKVT GCSLHPDILP NNAEDYRFIE TDIRNEADVK
     HLFEEVQPDV VINCSALSVP DYCETHHEEA YLTNVTAVGQ LADLCEEYKS RFIHLSTDFV
     FDGKINEAAG LLYTEEDLPA PVNYYGYTKW KGEERVAETC SSYAIVRVEI VYGKALPGQH
     GNIVQLVMNR LKAGQEIRVV SDQWRTPTYV GDVSDGVQRL IEHTTNGIFH ICGDECITIA
     EIAYQVADCM KLDRSLIHPA TTEEMNESTP RPRFSGMSID KARTMLGYRP QKLKEILANW
     NNL
//