ID E5CHC6_9BACE Unreviewed; 882 AA.
AC E5CHC6;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 13-JUN-2012, sequence version 2.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=alpha-L-rhamnosidase {ECO:0000256|ARBA:ARBA00012652};
DE EC=3.2.1.40 {ECO:0000256|ARBA:ARBA00012652};
GN ORFNames=BSGG_4849 {ECO:0000313|EMBL:EFS34149.2};
OS Bacteroides sp. D2.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=556259 {ECO:0000313|EMBL:EFS34149.2, ECO:0000313|Proteomes:UP000003135};
RN [1] {ECO:0000313|EMBL:EFS34149.2, ECO:0000313|Proteomes:UP000003135}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D2 {ECO:0000313|EMBL:EFS34149.2,
RC ECO:0000313|Proteomes:UP000003135};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Allen-Vercoe E., Strauss J.,
RA Sibley C., White A., Young S.K., Zeng Q., Gargeya S., Fitzgerald M.,
RA Haas B., Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Goldberg J.,
RA Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA MacDonald P.J.P., Montmayeur A., Murphy C., Neiman D., Pearson M.,
RA Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C.,
RA Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Bacteroides sp. D2.";
RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing alpha-L-rhamnose residues
CC in alpha-L-rhamnosides.; EC=3.2.1.40;
CC Evidence={ECO:0000256|ARBA:ARBA00001445};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFS34149.2}.
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DR EMBL; ACGA02000058; EFS34149.2; -; Genomic_DNA.
DR RefSeq; WP_009000219.1; NZ_JH636025.1.
DR AlphaFoldDB; E5CHC6; -.
DR HOGENOM; CLU_002926_1_1_10; -.
DR OrthoDB; 9766741at2; -.
DR Proteomes; UP000003135; Unassembled WGS sequence.
DR GO; GO:0030596; F:alpha-L-rhamnosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR016007; Alpha_rhamnosid.
DR InterPro; IPR035396; Bac_rhamnosid6H.
DR InterPro; IPR035398; Bac_rhamnosid_C.
DR InterPro; IPR013737; Bac_rhamnosid_N.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR008902; Rhamnosid_concanavalin.
DR PANTHER; PTHR33307; ALPHA-RHAMNOSIDASE (EUROFUNG); 1.
DR PANTHER; PTHR33307:SF6; ALPHA-RHAMNOSIDASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF05592; Bac_rhamnosid; 1.
DR Pfam; PF17389; Bac_rhamnosid6H; 1.
DR Pfam; PF17390; Bac_rhamnosid_C; 1.
DR Pfam; PF08531; Bac_rhamnosid_N; 1.
DR PIRSF; PIRSF010631; A-rhamnsds; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 166..337
FT /note="Bacterial alpha-L-rhamnosidase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08531"
FT DOMAIN 347..457
FT /note="Alpha-L-rhamnosidase concanavalin-like"
FT /evidence="ECO:0000259|Pfam:PF05592"
FT DOMAIN 462..789
FT /note="Alpha-L-rhamnosidase six-hairpin glycosidase"
FT /evidence="ECO:0000259|Pfam:PF17389"
FT DOMAIN 792..862
FT /note="Alpha-L-rhamnosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF17390"
SQ SEQUENCE 882 AA; 99264 MW; 5A4F5AD59150F928 CRC64;
MKRIVVILLG SLYGMVGIGA QEAMTPTALQ CEHLVNPLGI DATHPRFSWK LQSSRQGVTQ
HSYRIIVGTD SLAVTQGKGN SWDSGIVESD CTLSHYQGNK LLPFTRYFWK VQVEEQPDTL
QTSSKVQAFE TGMMKVDNWQ GAWITDRQSK EHHPSPYFRK VFHSGKPVKV ARAYIAVGGL
YELFLNGEKV GNHRLDPMLT RYDRRILYVT YDVTSHIRKG KNAIGVILGN GWYNHQALGV
WGFADAPWRN RPTFCLDLRL TYDDNTTEVV STGLDWRTSG GSIIRNNIYT GENQDADREQ
KGWNTANFDD SSWTDVSFRS APSQNIVAQQ LYPIRNVETI PAQYMNKLND SLYVFDLGRN
IAGVTQLKIE GKAGTIVRLI HAERLSPNGR VDLGRISNFH RPTDEEDLFQ TDTYILSGKG
KDTFMPKFNY KGFRYVEVSC SEPTELKKEC LTGYFMHNDV PEVGNVTTSD PIINKIWKAT
NVSYLSNLFG YPTDCPQREK NGWTGDGHLG IEAGLYNYDA LTIYEKWLAD HRDEQQPNGV
LPDIIPTSGW GYGTENGLDW TSTIALIPWN VYLFYGDSKL LEDCYENIKR YVDYVDRNSP
QYLSDWGRGD WVPVKTLSSK ELTSSVYYYV DTNILAHAAK LFGKQDDYEK YTALAENIKE
AINKKYLNRD TGIYAGGSQT ELSVPLMWGV VPEDMKAKVA ANLANKVQKD GCHVDVGVLG
CKALLNALSE NGYADLAFQV AAQKDYPSWG WWISNGATAL VENWDYQGAG EFSDNHMMFG
EIGAWFYKAL GGIKPDSEHP GFRHILLAPH FVKGLNYANI SYQSPSGLIV SNWKRKGKKI
IYEVTIPANC TATFTMPANI KDSRTVALEP GTHVFELQTT AK
//
