ID   E5DCZ9_LIRTU            Unreviewed;       688 AA.
AC   E5DCZ9;
DT   08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT   08-FEB-2011, sequence version 1.
DT   13-SEP-2023, entry version 43.
DE   RecName: Full=glycine--tRNA ligase {ECO:0000256|ARBA:ARBA00012829};
DE            EC=6.1.1.14 {ECO:0000256|ARBA:ARBA00012829};
DE   AltName: Full=Diadenosine tetraphosphate synthetase {ECO:0000256|ARBA:ARBA00030057};
OS   Liriodendron tulipifera (Tuliptree) (Tulip poplar).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Magnoliidae; Magnoliales; Magnoliaceae;
OC   Liriodendron.
OX   NCBI_TaxID=3415 {ECO:0000313|EMBL:ADR79437.1};
RN   [1] {ECO:0000313|EMBL:ADR79437.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Liang H., Barakat A., Schlarbaum S.E., Carlson J.E.;
RT   "Organization of the chromosome region harboring a FLORICAULA/LEAFY gene in
RT   Liriodendron.";
RL   Tree Genet. Genomes 7:373-384(2011).
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC   -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC       {ECO:0000256|ARBA:ARBA00008226}.
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DR   EMBL; GU252704; ADR79437.1; -; Genomic_DNA.
DR   AlphaFoldDB; E5DCZ9; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004820; F:glycine-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006426; P:glycyl-tRNA aminoacylation; IEA:InterPro.
DR   CDD; cd00774; GlyRS-like_core; 1.
DR   CDD; cd00858; GlyRS_anticodon; 1.
DR   Gene3D; 3.30.40.230; -; 1.
DR   Gene3D; 3.30.720.200; -; 1.
DR   Gene3D; 3.40.50.800; Anticodon-binding domain; 1.
DR   InterPro; IPR002314; aa-tRNA-synt_IIb.
DR   InterPro; IPR006195; aa-tRNA-synth_II.
DR   InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR   InterPro; IPR004154; Anticodon-bd.
DR   InterPro; IPR036621; Anticodon-bd_dom_sf.
DR   InterPro; IPR027031; Gly-tRNA_synthase/POLG2.
DR   InterPro; IPR033731; GlyRS-like_core.
DR   InterPro; IPR002315; tRNA-synt_gly.
DR   InterPro; IPR000738; WHEP-TRS_dom.
DR   NCBIfam; TIGR00389; glyS_dimeric; 1.
DR   PANTHER; PTHR10745:SF0; GLYCINE--TRNA LIGASE; 1.
DR   PANTHER; PTHR10745; GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2; 1.
DR   Pfam; PF03129; HGTP_anticodon; 1.
DR   Pfam; PF00587; tRNA-synt_2b; 1.
DR   PRINTS; PR01043; TRNASYNTHGLY.
DR   SMART; SM00991; WHEP-TRS; 1.
DR   SUPFAM; SSF52954; Class II aaRS ABD-related; 1.
DR   SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR   PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
DR   PROSITE; PS51185; WHEP_TRS_2; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW   ECO:0000313|EMBL:ADR79437.1}; ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          9..65
FT                   /note="WHEP-TRS"
FT                   /evidence="ECO:0000259|PROSITE:PS51185"
FT   DOMAIN          80..571
FT                   /note="Aminoacyl-transfer RNA synthetases class-II family
FT                   profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50862"
SQ   SEQUENCE   688 AA;  76201 MW;  48F6C142A977619B CRC64;
     MAEDDLRQSL ADKQAAVDAQ AAAVRDLKAQ GTAGSDLDAA VESLKALKLE AAAAASQLQA
     AVVASNGEGS SASREAFRQS VVNTLERRLF YIPSFKIYRG VAGLYDYGPP GCAVKSNVLA
     FWRQHFVLEE NMLEVDCPCV TPEVVLKASG HVDKFTDLMV KDEKTGTCYR ADHLLKDFCK
     EKLEKDLTLP AEKAAELKHV LAVLDDLSAE ELGAKLKEYG ITAPDTKNPL SDPYPFNLMF
     QTSIGPSGLS PGYMRPETAQ GIFVNFKDLY YYNGNKLPFA AAQIGQAFRN EISPRQGLLR
     VREFTLAEIE HFVDPDDKSH PKYKEVADLE FLMFPREEQL TGQAAKKLCL GEAVSTGTVN
     NQTLGYFIGR VYLFLTKLGI DKDRLRFRQH LPNEMAHYAA DCWDAEIECS YGWIECVGIA
     DRSAYDLRAH TEKSGVSLVA HEKYAEPREV EQLVIAPAKK EMGLAFKGSQ KMVVEALEAM
     NDAEAMEMKT ALESQGQVEF NVCTLGKTVM ITKNMVSISR QKKKEHQRVF TPSVIEPSFG
     IGRIIYCLFE HSFYMRASKA GDEQLNVFRF PSLVAPIKCT VFPLVQQQQY EEVAILISKS
     LTAAGISHKI DITGTSIGKR YARTDELGVP LAITVDSTSS VTIRERDSKD QIRVSINEVA
     SVVKEVTDGQ STWADVQWKY PAHTAGSE
//