ID E5KJU0_9EURY Unreviewed; 460 AA.
AC E5KJU0;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=CO-methylating acetyl-CoA synthase {ECO:0000256|ARBA:ARBA00012244};
DE EC=2.3.1.169 {ECO:0000256|ARBA:ARBA00012244};
OS Methanothrix harundinacea.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanotrichales; Methanotrichaceae; Methanothrix.
OX NCBI_TaxID=301375 {ECO:0000313|EMBL:ADQ42330.1};
RN [1] {ECO:0000313|EMBL:ADQ42330.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=6Ac {ECO:0000313|EMBL:ADQ42330.1};
RA Zhang G., Zhang F., Guo X., Ding G., Zhu J., Zhou L., Cai S., Liu X.,
RA Luo Y., Shi W., Dong X.;
RT "Quorum sensing in methanogenic archaeon.";
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: One-carbon metabolism; methanogenesis from acetate.
CC {ECO:0000256|ARBA:ARBA00004905}.
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DR EMBL; HQ188212; ADQ42330.1; -; Genomic_DNA.
DR AlphaFoldDB; E5KJU0; -.
DR OMA; YIEGIMH; -.
DR UniPathway; UPA00642; -.
DR GO; GO:0018492; F:carbon-monoxide dehydrogenase (acceptor) activity; IEA:InterPro.
DR GO; GO:0043884; F:CO-methylating acetyl-CoA synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006084; P:acetyl-CoA metabolic process; IEA:InterPro.
DR GO; GO:0019385; P:methanogenesis, from acetate; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.30.1650.10; Bifunctional carbon monoxide dehydrogenase/acetyl-coa synthase(codh/acs), Chain M, domain 3; 1.
DR Gene3D; 3.40.1470.10; Bifunctional carbon monoxide dehydrogenase/acetyl-coa synthase(codh/acs), Chain M, domain 5; 1.
DR Gene3D; 3.40.970.20; Carbon monoxide dehydrogenase alpha subunit. Chain D, domain 4; 1.
DR InterPro; IPR045822; ACS_CODH_B_C.
DR InterPro; IPR004461; CO_DH/Ac-CoA_synth_bsu.
DR InterPro; IPR038571; CO_DH/Ac-CoA_synth_bsu_3_sf.
DR InterPro; IPR011254; Prismane-like_sf.
DR NCBIfam; TIGR00316; cdhC; 1.
DR PANTHER; PTHR42281; -; 1.
DR PANTHER; PTHR42281:SF1; ACETYL-COA DECARBONYLASE_SYNTHASE COMPLEX SUBUNIT BETA 1; 1.
DR Pfam; PF19436; ACS_CODH_B_C; 1.
DR Pfam; PF03598; CdhC; 1.
DR SUPFAM; SSF56821; Prismane protein-like; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nickel {ECO:0000256|ARBA:ARBA00022596};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 162..391
FT /note="CO dehydrogenase/acetyl-CoA synthase complex beta
FT subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19436"
SQ SEQUENCE 460 AA; 51007 MW; B29D48765BC84900 CRC64;
MSPMYEGERI RKDEIWVEMG GPKAKAFELS VAGTMDEIQD GKVTVIGPDI SELEVGKTID
FGMIFKVAGE LIEKDLESII ERRNHALLSY IHGWMHLNQR DAIWMRAGLD LKKAGVTSFE
QIFKNVMTLY KAEMPFIEKM EVTILTDPAA VAKGLEQAHT AYHARDERAK GLHDEEVDVF
YGCTLCQAFA PTSACCVTPD RPSLCGAITW FDGRAAAKVD PEGPQFAIPK TGVIDEIAGE
YESVNEMAGS RSGGEYSRMA LYTFFDAPHT SCGCFETIGF YMPEVDGIGV VDRDFRNPTP
NGLPFSTMAG QAGGGKQVVG FLGMGILYYF SPKFLQADGG WRRIVWMPKQ LKERVKDGID
PEMYPKIATE EDAPDLAALK AFLLKVDHPV VDGVERKVDG KKVTEGWKVE DPSEYEEQVI
AFIEETGGDI DVDAIKAKLN MSEGQFMQVI EYLQNEGILE
//
