ID E5QYC3_ARTGP Unreviewed; 1113 AA.
AC E5QYC3;
DT 08-FEB-2011, integrated into UniProtKB/TrEMBL.
DT 08-FEB-2011, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
GN ORFNames=MGYG_00257 {ECO:0000313|EMBL:EFQ97215.1};
OS Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum
OS gypseum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Nannizzia.
OX NCBI_TaxID=535722 {ECO:0000313|Proteomes:UP000002669};
RN [1] {ECO:0000313|Proteomes:UP000002669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4604 / CBS 118893 {ECO:0000313|Proteomes:UP000002669};
RX PubMed=22951933; DOI=10.1128/mbio.00259-12;
RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W.,
RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E.,
RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I.,
RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., Summerbell R.C.,
RA Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., White T.C.;
RT "Comparative genome analysis of Trichophyton rubrum and related
RT dermatophytes reveals candidate genes involved in infection.";
RL MBio 3:E259-E259(2012).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCF family.
CC EF3 subfamily. {ECO:0000256|ARBA:ARBA00011054}.
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DR EMBL; DS989822; EFQ97215.1; -; Genomic_DNA.
DR RefSeq; XP_003176167.1; XM_003176119.1.
DR AlphaFoldDB; E5QYC3; -.
DR STRING; 535722.E5QYC3; -.
DR GeneID; 10031479; -.
DR VEuPathDB; FungiDB:MGYG_00257; -.
DR eggNOG; KOG0062; Eukaryota.
DR eggNOG; KOG1242; Eukaryota.
DR HOGENOM; CLU_002848_0_1_1; -.
DR InParanoid; E5QYC3; -.
DR OMA; EDHRKFG; -.
DR OrthoDB; 49929at2759; -.
DR Proteomes; UP000002669; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006338; P:chromatin remodeling; IEA:UniProt.
DR CDD; cd03221; ABCF_EF-3; 1.
DR CDD; cd18626; CD_eEF3; 1.
DR Gene3D; 2.40.50.990; -; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR023780; Chromo_domain.
DR InterPro; IPR015688; eEF3_ABC2_chromodomain-like.
DR InterPro; IPR047038; eEF3_chromodomain-like_sf.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19211:SF14; ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 3; 1.
DR PANTHER; PTHR19211; ATP-BINDING TRANSPORT PROTEIN-RELATED; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF00385; Chromo; 1.
DR SMART; SM00382; AAA; 2.
DR SMART; SM00298; CHROMO; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002669};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT REPEAT 218..256
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT DOMAIN 482..700
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 726..1043
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1051..1113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1080..1095
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1113 AA; 123116 MW; 8B56C2F1E31A10A3 CRC64;
MPLLETASMQ SERIVPVASK AADGAVRDDV AHLLRTIFEA QTSQQALDAS YGLTNLLIST
GSVRCLHTFN VIPEIKKAAT DKKNGARRES SMLILGALFE QYPLKNPLSE VIFLLEDGGL
LYLALDLLAD KGAVVREAAQ YAIDALFACL KEESLVHALV EPLSRYLNKP TGKWQGTVGA
YKLLEKVAKR AEIGTDSKEK EELKDLLRLT LGQKLKDLIP IVESGMHDLK AEVAKQAVKT
MTALSTVLDN DDVATRIPLL LKTMEKPSTE TLQKAIHALS QTTFVAIVTS PVLALLTPLL
ERSLNTPTTT QEVLRQTVVV VENLTRLVHD PVEARTFLPK LKPGVQRVKD GASLPEVREL
ATRAMNVIDK AMGDDEAGTT DSRATTEQVE AVLEEQMKPY SNFSGTDEKR FWETSRNYIA
NMIRDDANSR LLERIPVCVG PYLQSFVPDG RHDEIAAAVK AHFVAEDERR FGVPVKEDDG
EIEIVNANFS LGYGGRLLLS HANLRLLKGH RYGLCGRNGV GKSTLMRSIA NGKLEGFPPQ
DVLKTCFVEH NQGEDAELSV LEFVTKDPEM AAAGEEKISA ALNEVGFTPG PEGRQQQPVG
SLSGGWKMKL ALARAMVMGA DVLLLDEPTN HLDVHNVKWL QEYLKKHTEV TSLIVSHDSG
FLDEVCTDIY HYEQKKLVHY KGNLADFVKV KPEAKSYYTL SSANANFKFP PPGILSGVKS
STRIILRMTN CSYTYPGSSK PSLVDASCAL TLSSRVAIIG GNGAGKSTLM KLLTGETIPQ
TGKVEKHPNL RIGYIKQHAL EHVEMHMEKT PNQYLQWRYA NGDDREVLMK QTRILTEEDK
IQMAKPVDIG DGKGPRNIEA LMGRQKYKKT FQYEVKWKNM LPKHNTQISR ETLLQLGFQK
LVQEFDDHEA SREGLGYRVL EPKVISKHFE DIGLDPEIAN HNEIGGLSGG QKVKVVLAGA
MWNNPHLLVL DEPTNFLDRD FLGGLAVAIR EFKGGVVMIS HNDEFVGALC PERWYVENGR
MTHGGTTAVA LDRFEDQSRN PSTVASSVVS SAAPSAVNSG AEDGGELKFK AKKKKKMTRA
QLKEREVRRR LRHIEWLNSP AGTPHPPDTD DEQ
//
