ID E5V7E7_9BACE Unreviewed; 501 AA.
AC E5V7E7;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DXB40_03360 {ECO:0000313|EMBL:RGN85537.1}, DXD65_12540
GN {ECO:0000313|EMBL:RGJ32643.1}, HMPREF1007_00680
GN {ECO:0000313|EMBL:EFV27228.1};
OS Bacteroides sp. 4_1_36.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=457393 {ECO:0000313|EMBL:EFV27228.1, ECO:0000313|Proteomes:UP000004735};
RN [1] {ECO:0000313|EMBL:EFV27228.1, ECO:0000313|Proteomes:UP000004735}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4_1_36 {ECO:0000313|EMBL:EFV27228.1,
RC ECO:0000313|Proteomes:UP000004735};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Earl A., Feldgarden M., Young S.K., Gargeya S., Zeng Q.,
RA Alvarado L., Berlin A., Bochicchio J., Chapman S.B., Chen Z., Freedman E.,
RA Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D.,
RA Howarth C., Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., White J., Yandava C.,
RA Allen-Vercoe E., Sibley C., Strauss J., Daigneault M., Haas B., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Bacteroides sp. strain 4_1_36.";
RL Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000261007, ECO:0000313|Proteomes:UP000263804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OM03-9 {ECO:0000313|EMBL:RGN85537.1,
RC ECO:0000313|Proteomes:UP000261007}, and TM07-1
RC {ECO:0000313|EMBL:RGJ32643.1, ECO:0000313|Proteomes:UP000263804};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFV27228.1}.
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DR EMBL; ACTC01000033; EFV27228.1; -; Genomic_DNA.
DR EMBL; QSOX01000012; RGJ32643.1; -; Genomic_DNA.
DR EMBL; QSUY01000005; RGN85537.1; -; Genomic_DNA.
DR RefSeq; WP_005830555.1; NZ_QSOX01000012.1.
DR AlphaFoldDB; E5V7E7; -.
DR HOGENOM; CLU_042501_0_0_10; -.
DR Proteomes; UP000004735; Unassembled WGS sequence.
DR Proteomes; UP000261007; Unassembled WGS sequence.
DR Proteomes; UP000263804; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:RGJ32643.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000313|EMBL:RGJ32643.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..501
FT /note="histidine kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5033695977"
FT TRANSMEM 259..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 339..501
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 501 AA; 56464 MW; 51C0472494D57DE7 CRC64;
MKKIISILLL ATFCIFTQLH AQNRADELMK QAQENLTKKE YIKARYLFLQ AYNAFATQDK
YAQAVECGVN ASALYHRENY YKEAFELLRG AEQVVATGEQ KTGKAMPNLR FRINKERLQM
YINLKNPARA KEQLTKLEET AKASHNDSLS NDLLYTQANY YYTFGMNTQG DAATNRLIGQ
YKEQKNYAKV DECYKTLISI ARKANNAGLV ARTYDKYILW TDSVKALTAQ EELNALKKKY
DESLATIQEK DDSLSAKQYI IIGLCILAAI LAAALVFGAI VLLRFIILTR KQKKAISIAN
EHNELKTKFI QNISAQMEPT LDTLDASLPG VKALHAFSNH IQELSELETT LSEPYEVQEK
NISTFCEGIM DKIKGMTQED VTLTVNAPKL NVKINPEQLE RVLLHLLENA AEYTPAGGKI
WLDFKKRGAH THQFIISDTG CGIPEEQREN IFKPFTEVKD LTQGDGLGLP ICSLIATKMN
GSLTLDSSYN KGARFVLELH A
//
