ID E5VFV5_9BACE Unreviewed; 508 AA.
AC E5VFV5;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 24-JAN-2024, entry version 63.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=DXB40_18225 {ECO:0000313|EMBL:RGN80671.1}, HMPREF1007_03641
GN {ECO:0000313|EMBL:EFV24254.1};
OS Bacteroides sp. 4_1_36.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=457393 {ECO:0000313|EMBL:EFV24254.1, ECO:0000313|Proteomes:UP000004735};
RN [1] {ECO:0000313|EMBL:EFV24254.1, ECO:0000313|Proteomes:UP000004735}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4_1_36 {ECO:0000313|EMBL:EFV24254.1,
RC ECO:0000313|Proteomes:UP000004735};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Earl A., Feldgarden M., Young S.K., Gargeya S., Zeng Q.,
RA Alvarado L., Berlin A., Bochicchio J., Chapman S.B., Chen Z., Freedman E.,
RA Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D.,
RA Howarth C., Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., White J., Yandava C.,
RA Allen-Vercoe E., Sibley C., Strauss J., Daigneault M., Haas B., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Bacteroides sp. strain 4_1_36.";
RL Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:RGN80671.1, ECO:0000313|Proteomes:UP000261007}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OM03-9 {ECO:0000313|EMBL:RGN80671.1,
RC ECO:0000313|Proteomes:UP000261007};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFV24254.1}.
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DR EMBL; ACTC01000130; EFV24254.1; -; Genomic_DNA.
DR EMBL; QSUY01000053; RGN80671.1; -; Genomic_DNA.
DR RefSeq; WP_005828859.1; NZ_GL622510.1.
DR AlphaFoldDB; E5VFV5; -.
DR HOGENOM; CLU_000445_89_13_10; -.
DR Proteomes; UP000004735; Unassembled WGS sequence.
DR Proteomes; UP000261007; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:RGN80671.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000313|EMBL:RGN80671.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 291..502
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 508 AA; 58412 MW; F9FCE8A5DB94A348 CRC64;
MHLTLFGEVQ LFLLIAVTSA SFLYWINHKY KSLNRQIIRA IDIPVYLLNR QGIVVKLLNT
PTEKANRLPF LNPGVLNINN LVTDADECRK YMTSLLRVLN TRTSDSLTLK IRIESGEKLY
IAVRMVYLNR NYVIAFIRDI TEDEVQRREN EKYRFFLESI LENLPIATTV KDKNDEGRYL
IWNKKAAEMM EVPAEDIVGH YEEEFNPLMQ DNFIQETDKE VEESEIPQSY IKHFVNPKGR
EYILSFHKTL VSYNKGKERW IVSSALDITE LLAAKEKAEE ANRLKSAFLA NMSHEIRTPL
NAIVGFSSIL SDYIQDEDTK EYIHIIEENT QLLLQLINDI LDLSRIEAGI LEFTEGDMDV
NKTLDEMQTM AKLKLPSEVS IRLLPGADYC IIHTVPKRVR QVLNNYLSNA LKHTEEGFID
IGYHLPQEDR IRFFVRDTGC GIPPEKQKDV FERFVKLNSF KQGTGLGLSI CTMIAEKMNG
KVGVSSIPGK GSEFWFEIPY QPAGSQPA
//
