ID   E5YCP4_9ENTR            Unreviewed;       248 AA.
AC   E5YCP4;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Protein sanA {ECO:0000313|EMBL:EFV42188.1};
GN   ORFNames=HMPREF0864_00517 {ECO:0000313|EMBL:EFV42188.1};
OS   Enterobacteriaceae bacterium 9_2_54FAA.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae.
OX   NCBI_TaxID=469613 {ECO:0000313|EMBL:EFV42188.1, ECO:0000313|Proteomes:UP000004908};
RN   [1] {ECO:0000313|EMBL:EFV42188.1, ECO:0000313|Proteomes:UP000004908}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=9_2_54FAA {ECO:0000313|EMBL:EFV42188.1,
RC   ECO:0000313|Proteomes:UP000004908};
RG   The Broad Institute Genome Sequencing Platform;
RA   Ward D., Earl A., Feldgarden M., Young S.K., Gargeya S., Zeng Q.,
RA   Alvarado L., Berlin A., Bochicchio J., Chapman S.B., Chen Z., Freedman E.,
RA   Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E., Heiman D.,
RA   Howarth C., Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T.,
RA   Shenoy N., Sisk P., Stolte C., Sykes S., White J., Yandava C.,
RA   Allen-Vercoe E., Ambrose C., Strauss J., Sibley C., Haas B., Nusbaum C.,
RA   Birren B.;
RL   Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EFV42188.1, ECO:0000313|Proteomes:UP000004908}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=9_2_54FAA {ECO:0000313|EMBL:EFV42188.1,
RC   ECO:0000313|Proteomes:UP000004908};
RG   The Broad Institute Genomics Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Allen-Vercoe E., Ambrose C.,
RA   Strauss J., Sibley C., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Enterobacteriaceae bacterium 9_2_54FAA.";
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Participates in the barrier function of the cell envelope.
CC       {ECO:0000256|ARBA:ARBA00037355}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|ARBA:ARBA00004377}; Single-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004377}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004167}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFV42188.1}.
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DR   EMBL; ADCU02000001; EFV42188.1; -; Genomic_DNA.
DR   AlphaFoldDB; E5YCP4; -.
DR   Proteomes; UP000004908; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd06259; YdcF-like; 1.
DR   InterPro; IPR003848; DUF218.
DR   InterPro; IPR023604; Uncharacterised_SanA.
DR   PANTHER; PTHR30336; INNER MEMBRANE PROTEIN, PROBABLE PERMEASE; 1.
DR   PANTHER; PTHR30336:SF0; PROTEIN SANA; 1.
DR   Pfam; PF02698; DUF218; 1.
DR   PIRSF; PIRSF005011; SanA; 1.
PE   4: Predicted;
KW   Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          47..171
FT                   /note="DUF218"
FT                   /evidence="ECO:0000259|Pfam:PF02698"
SQ   SEQUENCE   248 AA;  28068 MW;  97B94970BA7FB330 CRC64;
     MWRRLIYGIL TVAILLAVTA IGLDRWISWK TAPYIYEEVQ DLPHRQVGVV LGTAKYVSTG
     TINQYYRYRI QGALNAYNSN KVNYLLLSGD NALESYNEPV TMRRDLITAG VPSGDIVLDY
     AGFRTLDSIV RTRKVFDTND FTIITQRFHC ERALFIALHM GIQAQCLAVP SPKNMMMIRI
     REIGARLGAL TDLYILKREP RFLGPMIPIP AVHKVPADAQ SYPAVSPEQL QELEQVLQKE
     KNADKPAE
//