ID E6KIK8_STROR Unreviewed; 240 AA.
AC E6KIK8;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Segregation and condensation protein A {ECO:0000256|HAMAP-Rule:MF_01805};
GN Name=scpA {ECO:0000256|HAMAP-Rule:MF_01805};
GN ORFNames=HMPREF8578_0073 {ECO:0000313|EMBL:EFU64216.1};
OS Streptococcus oralis ATCC 49296.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=888049 {ECO:0000313|EMBL:EFU64216.1, ECO:0000313|Proteomes:UP000004500};
RN [1] {ECO:0000313|EMBL:EFU64216.1, ECO:0000313|Proteomes:UP000004500}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49296 {ECO:0000313|EMBL:EFU64216.1,
RC ECO:0000313|Proteomes:UP000004500};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Participates in chromosomal partition during cell division.
CC May act via the formation of a condensin-like complex containing Smc
CC and ScpB that pull DNA away from mid-cell into both cell halves.
CC {ECO:0000256|HAMAP-Rule:MF_01805}.
CC -!- SUBUNIT: Component of a cohesin-like complex composed of ScpA, ScpB and
CC the Smc homodimer, in which ScpA and ScpB bind to the head domain of
CC Smc. The presence of the three proteins is required for the association
CC of the complex with DNA. {ECO:0000256|HAMAP-Rule:MF_01805}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01805}.
CC Note=Associated with two foci at the outer edges of the nucleoid region
CC in young cells, and at four foci within both cell halves in older
CC cells. {ECO:0000256|HAMAP-Rule:MF_01805}.
CC -!- SIMILARITY: Belongs to the ScpA family. {ECO:0000256|HAMAP-
CC Rule:MF_01805}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFU64216.1}.
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DR EMBL; AEPO01000001; EFU64216.1; -; Genomic_DNA.
DR RefSeq; WP_000351884.1; NZ_GL622183.1.
DR AlphaFoldDB; E6KIK8; -.
DR eggNOG; COG1354; Bacteria.
DR HOGENOM; CLU_038686_3_3_9; -.
DR Proteomes; UP000004500; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR Gene3D; 6.10.250.2410; -; 1.
DR Gene3D; 1.10.10.580; Structural maintenance of chromosome 1. Chain E; 1.
DR HAMAP; MF_01805; ScpA; 1.
DR InterPro; IPR003768; ScpA.
DR InterPro; IPR023093; ScpA-like_C.
DR PANTHER; PTHR33969; SEGREGATION AND CONDENSATION PROTEIN A; 1.
DR PANTHER; PTHR33969:SF2; SEGREGATION AND CONDENSATION PROTEIN A; 1.
DR Pfam; PF02616; SMC_ScpA; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|HAMAP-Rule:MF_01805};
KW Cell division {ECO:0000256|HAMAP-Rule:MF_01805};
KW Chromosome partition {ECO:0000256|ARBA:ARBA00022829, ECO:0000256|HAMAP-
KW Rule:MF_01805}; Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01805}.
SQ SEQUENCE 240 AA; 28060 MW; 215A2380DF4A593A CRC64;
MDIKLKDFEG PLDLLLHLVS KYQMDIYDVP ITEVIEQYLA YVSTLQAMRL EVTGEYMVMA
SQLMLIKSRK LLPKVAEVTD LEDDLEQDLL SQIEEYRKFK LLGEHLEAKH QDRAQYYSKA
PTELIYEDAE LVHDKTTIDL FLAFSNILAK KKEEFAQNHT TILRDEYKIE DMMVIVKESL
AGRDQLRLQD LFKEAQNVQE VITLFLATLE LIKTQELILV QEESFGDIYL MEKKEESQEA
//
