ID E6KYS6_9PAST Unreviewed; 498 AA.
AC E6KYS6;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|SMART:SM00327};
GN ORFNames=HMPREF9064_1308 {ECO:0000313|EMBL:EFU67353.1};
OS Aggregatibacter segnis ATCC 33393.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Aggregatibacter.
OX NCBI_TaxID=888057 {ECO:0000313|EMBL:EFU67353.1, ECO:0000313|Proteomes:UP000032871};
RN [1] {ECO:0000313|EMBL:EFU67353.1, ECO:0000313|Proteomes:UP000032871}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33393 {ECO:0000313|EMBL:EFU67353.1,
RC ECO:0000313|Proteomes:UP000032871};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFU67353.1}.
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DR EMBL; AEPS01000008; EFU67353.1; -; Genomic_DNA.
DR RefSeq; WP_006718901.1; NZ_LS483443.1.
DR AlphaFoldDB; E6KYS6; -.
DR GeneID; 60800692; -.
DR HOGENOM; CLU_032208_1_0_6; -.
DR OrthoDB; 5755451at2; -.
DR Proteomes; UP000032871; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR Pfam; PF00092; VWA; 1.
DR PRINTS; PR01217; PRICHEXTENSN.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000032871};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 158..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 279..484
FT /note="VWFA"
FT /evidence="ECO:0000259|SMART:SM00327"
FT REGION 188..267
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..267
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 498 AA; 55535 MW; F5EB4435003D089F CRC64;
MQRLARVNLD QQNSAAVELF GHYNEITAIL LRHLPPSTAS MLARPEVHGE VVEWYSELQG
QPYLLGNSER DQQARKQAET FISHRLATVD KLRAELVQKG SINAEQATLL ERVVDAAQHD
SIQIYIVNKQ PVMTGWGLGE KPIPVPPPVV PAPSKSLGWL WLLPLLLLLL GGLAWWLFFR
PEPVQSQPME PVKVEISKPE PPKEEPKPEP PKEELKPEPQ RLEFIPEPEE PSKVEEPPKV
EEPPKVEEPP KVEDPPKVEE PPKQEKPKYC TKTITPAQRP QMVIVFDDSL SMLASLNESS
AVINAFWDRW NNNEIISEEE KVHMFREPRR LTTAKKAATD IIDKIDPNID IGLVSLRRCP
GARNHGMFGP SKRKALKAQI RGLFPKEGEE NIGTALHSGL RQAAAMVDGV KRDAFILVLS
DGEESCDKGN TNVCAIAQEL AKQKPKLKIN VVDIGGAKAA NCLATETKGK VFTANSKAQV
TNMINQAIKP MVEKEECK
//
