ID E6LKW3_9FIRM Unreviewed; 463 AA.
AC E6LKW3;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=ATP-dependent Clp protease, ATP-binding subunit ClpX {ECO:0000313|EMBL:EFU77509.1};
GN Name=clpX {ECO:0000313|EMBL:EFU77509.1};
GN ORFNames=HMPREF0381_0598 {ECO:0000313|EMBL:EFU77509.1};
OS Lachnoanaerobaculum saburreum DSM 3986.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Lachnoanaerobaculum.
OX NCBI_TaxID=887325 {ECO:0000313|EMBL:EFU77509.1, ECO:0000313|Proteomes:UP000003434};
RN [1] {ECO:0000313|EMBL:EFU77509.1, ECO:0000313|Proteomes:UP000003434}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 3986 {ECO:0000313|EMBL:EFU77509.1,
RC ECO:0000313|Proteomes:UP000003434};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFU77509.1}.
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DR EMBL; AEPW01000014; EFU77509.1; -; Genomic_DNA.
DR RefSeq; WP_008750368.1; NZ_GL622296.1.
DR AlphaFoldDB; E6LKW3; -.
DR eggNOG; COG1219; Bacteria.
DR HOGENOM; CLU_014218_8_2_9; -.
DR Proteomes; UP000003434; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR004487; Clp_protease_ATP-bd_su_ClpX.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010603; Znf_CppX_C4.
DR NCBIfam; TIGR00382; clpX; 1.
DR PANTHER; PTHR48102:SF7; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR48102; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR Pfam; PF06689; zf-C4_ClpX; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:EFU77509.1};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Hydrolase {ECO:0000313|EMBL:EFU77509.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protease {ECO:0000313|EMBL:EFU77509.1};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 162..321
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 364..459
FT /note="Clp ATPase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01086"
SQ SEQUENCE 463 AA; 52184 MW; 8C10BFAC3DE8C644 CRC64;
MEDKIEYNTK DKDDKSGNYE KICYMCRRPE SKTGAMISMP GGIDICPDCI QKTFNSMQSM
DMSKLSGITN IDDIKNIDLS SLNIPNMNVN PIPERARVKK RDKKRTEPLF TMKDVPAPHK
IKEMLDEYVI GQDVAKKVIS VAVYNHYKRI FLDKDKEGTR IEKSNILMIG PTGSGKTYLV
KTLAKLLNVP LAIADATSLT EAGYIGDDIE SVISKLLLSA GNDVERAECG IVFIDEIDKI
AKKKNTNTRD VSGESVQQEL LKLLEGSKVE VPVGTNQKNV LAPMETVNTD NILFICGGAF
PALDDIIKER LQKNTSVGFN SELKDKYDNE TDLYSKVTNE DIRKFGMIPE FIGRLPVICT
LSKLDKDAFK KILNEPKNAI LKQYKRLLEL DEVELVFDDD ATDYIAEQAM KKDTGARALR
SIIEEFMLDI MYEIPKDKNI GRVIITRDYL EHKGAPNIVF RNV
//
