ID E6LY41_9ACTO Unreviewed; 644 AA.
AC E6LY41;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=DNA (Cytosine-5-)-methyltransferase {ECO:0000313|EMBL:EFU80558.1};
GN ORFNames=HMPREF0388_0778 {ECO:0000313|EMBL:EFU80558.1};
OS Mobiluncus curtisii ATCC 51333.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Mobiluncus.
OX NCBI_TaxID=887326 {ECO:0000313|EMBL:EFU80558.1, ECO:0000313|Proteomes:UP000005573};
RN [1] {ECO:0000313|EMBL:EFU80558.1, ECO:0000313|Proteomes:UP000005573}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51333 {ECO:0000313|EMBL:EFU80558.1,
RC ECO:0000313|Proteomes:UP000005573};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the N(4)/N(6)-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00006594}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFU80558.1}.
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DR EMBL; AEPY01000004; EFU80558.1; -; Genomic_DNA.
DR RefSeq; WP_004009209.1; NZ_GL622340.1.
DR AlphaFoldDB; E6LY41; -.
DR HOGENOM; CLU_020164_1_1_11; -.
DR Proteomes; UP000005573; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002941; DNA_methylase_N4/N6.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR002295; N4/N6-MTase_EcoPI_Mod-like.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR13370; RNA METHYLASE-RELATED; 1.
DR PANTHER; PTHR13370:SF16; TYPE III RESTRICTION-MODIFICATION ENZYME STYLTI MOD SUBUNIT; 1.
DR Pfam; PF01555; N6_N4_Mtase; 1.
DR PRINTS; PR00506; D21N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:EFU80558.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EFU80558.1}.
FT DOMAIN 66..437
FT /note="DNA methylase N-4/N-6"
FT /evidence="ECO:0000259|Pfam:PF01555"
SQ SEQUENCE 644 AA; 72351 MW; 4D8852AF649B2FB7 CRC64;
MPELNWVGKN KVINHHLDVP YRVLERQYSF DTDGQHKVDN GSNNMIIHGD NLEALKSLLP
RYDGQVDVIY IDPPYNTGNE GWVYNDAVND PQIKKWLGEV VGKEGEDLSR HDKWLCMMYP
RLRLLQRLLA PTGAIFISID DNEAANLRLI GNEIFGARCF VADISWQRTY STRNDSKGIP
AEVEHLLVFS KQPDWQPNKL ERTAEMDSKY KNPDNDRSPW RTDNAFAPGA RTHQGMVYAI
QHPFTGELLY PAINNCWRYQ QDEMFSIMSG WTDYELVDLY DEAERAKVCG VKAEEVREGV
KAIMLAKPLE QARLDAQAVL ARGQWPRFFF TKNGEGGIAR KTYLDSVGGL LPTNYWSHVE
AGHTDEAKKE IQELFDGAVA FDTPKPTRLI ERVLKVASSP HSIVLDSFAG SGTTAHAVLS
LNKKDGGNRQ FILVELGDYA DSVTAERVKR VARGYTATKS VKTTLYDEKL TTAMLKKGEK
VFAEAKAIAD GAKDQYEKVT GPSVKDGQLQ VVAQTSAKED VPGLGGDFSF YELGPELIAE
GNLNPDVPVA QVRDYIWFTE TRRAIPDDSS SNPYYLGSAN GAVYYFIYEP DAVTVLDRAF
LATMDPNHRG ESYIVYADLC ELSAEEMTKL GIVFKKIPRD ITRL
//
