ID E6M2U4_9ACTO Unreviewed; 816 AA.
AC E6M2U4;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 24-JAN-2024, entry version 47.
DE SubName: Full=DEAD/DEAH box helicase {ECO:0000313|EMBL:EFU82280.1};
GN ORFNames=HMPREF0576_0649 {ECO:0000313|EMBL:EFU82280.1};
OS Mobiluncus holmesii ATCC 35242.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Mobiluncus.
OX NCBI_TaxID=887899 {ECO:0000313|EMBL:EFU82280.1, ECO:0000313|Proteomes:UP000003343};
RN [1] {ECO:0000313|EMBL:EFU82280.1, ECO:0000313|Proteomes:UP000003343}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35242 {ECO:0000313|EMBL:EFU82280.1,
RC ECO:0000313|Proteomes:UP000003343};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFU82280.1}.
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DR EMBL; AEPZ01000005; EFU82280.1; -; Genomic_DNA.
DR RefSeq; WP_004010674.1; NZ_GL622346.1.
DR AlphaFoldDB; E6M2U4; -.
DR HOGENOM; CLU_002902_4_1_11; -.
DR Proteomes; UP000003343; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.3380.30; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:EFU82280.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 66..223
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 329..488
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 552..578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 563..577
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 816 AA; 90302 MW; 16D2211C44AA9CB0 CRC64;
MSPKRHRYRE SQKAAARLAQ TEAANATSPS PAQRYQAFKA TQQSPQLYEF QALFDFPLDD
FQIEACQVLD KGQDVLVSAP TSAGKTIVGL YGIFLALRQG KRLFYTTPIK ALSNQKYLEL
VELFGVDNVG LLTGDTAING DAAIIVMTTE VLRNMIYAAA PLADLGYVVM DEVHYLSDHF
RGPVWEEIII HLDAAVRLIS LSATISNANV FAQWLQTLRG PTTVISTSVR PVPLKHFMIS
ASGEILPLFA KGEVGGHLNR ALLAQAAQQV MPRRGRMPRR IRADRPAVAR SLEQRDLLPA
IVFIFSRQGC NDAAAQVFDA GLRFTTPQEA DQIRLEVETT LAGFSQGDLS AIDVSNWEET
LAAGIAPHHA GLLPIQKQLT ESLFAKGLIR LVFATETLAL GINMPARTVV LESLNKWNGQ
ERANLTPGEY TQLTGRAGRR GIDSVGHALT LMEVKNPPQL LANLASQQTY PLHSAFVPTF
NMAVNLLART TLEGAKETVE KSFAQYVALG SSRKLFAQLR RFEDLAADQE RSASCERGDV
MALLDLMNAL SKTEKQAKQR RHSGENTPQN QQADRRAIEQ ARAQMKAHPV YSCPERDKHL
VKARQAAKNR ESARITRQRI ETRTKSLARQ LDHTCQVLRE LDYVDDNFQL RDAGIMLQSV
YNERDLLVVE CLRRGVFDDL NVADLAGALS VCLAQNRTGG LSRLIPAEAS ANLATALESM
GRINFEIATL QQEHYLEAYP PLETDLLPGV VAWAQDVTLG QCLELTGMSA GDFVRVIRQV
IDLADQLRKL NLNPALHAKF RSVINQVKRG VVTWDF
//
