ID E6MJA8_9FIRM Unreviewed; 461 AA.
AC E6MJA8;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Glutamate synthase (NADPH), homotetrameric {ECO:0000313|EMBL:EFV00928.1};
DE EC=1.4.1.13 {ECO:0000313|EMBL:EFV00928.1};
GN Name=gltA {ECO:0000313|EMBL:EFV00928.1};
GN ORFNames=HMP0721_2093 {ECO:0000313|EMBL:EFV00928.1};
OS Pseudoramibacter alactolyticus ATCC 23263.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC Pseudoramibacter.
OX NCBI_TaxID=887929 {ECO:0000313|EMBL:EFV00928.1, ECO:0000313|Proteomes:UP000004754};
RN [1] {ECO:0000313|EMBL:EFV00928.1, ECO:0000313|Proteomes:UP000004754}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23263 {ECO:0000313|EMBL:EFV00928.1,
RC ECO:0000313|Proteomes:UP000004754};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFV00928.1}.
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DR EMBL; AEQN01000026; EFV00928.1; -; Genomic_DNA.
DR RefSeq; WP_006599515.1; NZ_GL622359.1.
DR AlphaFoldDB; E6MJA8; -.
DR STRING; 887929.HMP0721_2093; -.
DR eggNOG; COG0493; Bacteria.
DR HOGENOM; CLU_000422_3_3_9; -.
DR Proteomes; UP000004754; Unassembled WGS sequence.
DR GO; GO:0004355; F:glutamate synthase (NADPH) activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR Gene3D; 1.10.1060.10; Alpha-helical ferredoxin; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR028261; DPD_II.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR009051; Helical_ferredxn.
DR InterPro; IPR006004; SudA-like.
DR NCBIfam; TIGR01316; gltA; 1.
DR PANTHER; PTHR43100; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR PANTHER; PTHR43100:SF1; GLUTAMATE SYNTHASE [NADPH] SMALL CHAIN; 1.
DR Pfam; PF14691; Fer4_20; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF51971; Nucleotide-binding domain; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:EFV00928.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004754}.
FT DOMAIN 19..129
FT /note="Dihydroprymidine dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF14691"
FT DOMAIN 141..447
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
SQ SEQUENCE 461 AA; 49558 MW; 54A193E30DE9A21B CRC64;
MAKKRMDRVP VREQDPKARA TNFEEVCYGY NEAEAVEEAN RCLNCKKPRC VAGCPVSIDI
PGFIHEVTEK NYQKAFEIIQ ESSLLPAVCG RVCPQESQCE GPCVMGIKGD AVAIGKLERF
VADWARENNI VPEKPGFVSG KKVAIIGSGP AGLTCAAELA KKGHDVTIFE ALHEAGGVLV
YGIPEFRLPK EAVVAAEVEN VKRLGVKIET DVVIGKATTI DELMDEEGFD AVFIGSGAGL
PRFMGIPGET ANGVFSANEY LTRNNLMKAF KGYDTPIHRG KKVAVIGGGN VAMDAARSAL
RLGADTYIVY RRSEAELPAR AEEVHHAKEE GIEFHLLTNP KAILVNEDGW VKGLRVIKMK
LGEPDESGRR RPIEIPGSEY DLEVDTVIMA LGTSPNPLIS STTEGLDTNR WQCIVADENG
QTSRKGIFAG GDAVSGAATV ILAMGAGKDA AAAINDYLNT L
//
