ID   E6PET2_9ZZZZ            Unreviewed;       343 AA.
AC   E6PET2;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Crp/Fnr family transcriptional regulator {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CARN1_0143 {ECO:0000313|EMBL:CBH74968.1};
OS   mine drainage metagenome.
OC   unclassified sequences; metagenomes; ecological metagenomes.
OX   NCBI_TaxID=410659 {ECO:0000313|EMBL:CBH74968.1};
RN   [1] {ECO:0000313|EMBL:CBH74968.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Bertin P.N., Heinrich-Salmeron A., Pelletier E., Goulhen-Chollet F.,
RA   Arsene-Ploetze F., Gallien S., Calteau A., Vallenet D., Casiot C.,
RA   Chane-Woon-Ming B., Giloteaux L., Barakat M., Bonnefoy V., Bruneel O.,
RA   Chandler M., Cleiss J., Duran R., Elbaz-Poulichet F., Fonknechten N.,
RA   Lauga B., Mornico D., Ortet P., Schaeffer C., Siguier P.,
RA   Alexander Thil Smith A., Van Dorsselaer A., Weissenbach J., Medigue C.,
RA   Le Paslier D.;
RT   "Diversity of trophic interactions inside an arsenic-rich microbial
RT   ecosystem.";
RL   Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CBH74968.1}.
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DR   EMBL; CABL01000005; CBH74968.1; -; Genomic_DNA.
DR   AlphaFoldDB; E6PET2; -.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd00038; CAP_ED; 1.
DR   Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000595; cNMP-bd_dom.
DR   InterPro; IPR018490; cNMP-bd_dom_sf.
DR   InterPro; IPR012318; HTH_CRP.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR24567; CRP FAMILY TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR   PANTHER; PTHR24567:SF74; REGULATORY PROTEIN CYSR HOMOLOG; 1.
DR   Pfam; PF00027; cNMP_binding; 1.
DR   Pfam; PF13545; HTH_Crp_2; 1.
DR   SMART; SM00100; cNMP; 1.
DR   SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50042; CNMP_BINDING_3; 1.
DR   PROSITE; PS51063; HTH_CRP_2; 1.
PE   4: Predicted;
FT   DOMAIN          115..235
FT                   /note="Cyclic nucleotide-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50042"
FT   DOMAIN          249..323
FT                   /note="HTH crp-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51063"
SQ   SEQUENCE   343 AA;  38440 MW;  9EEB1EF8AA5D9769 CRC64;
     MHRGAKAMDT RAQNSLSRER VVLYVGAACP FSDLAVERVR RVLDEYPALT LSVRERARAH
     DDGVPLVATP TLLLSDGRRL TGTPSEERLH RVFSALLGKS IPMANKVWYI ERNRLFHGVP
     REEIERFAHL FHERDYGAKE IVFSQGDLGD AIYLLKSGHV RLFRSTEDGK ELTLAILGPG
     DVFGELALFD ESRRQTFAEA LDAAHICAAS VDDFTRLMGH RPTLTMMVAG EMARRRREIE
     TRIAGLAYGS VRARLQHALR HLAREHGEAL EGGEVRIAVR LSHQELAQLI GTSRETCTLE
     LGKLQLAGCL RVDDERNFIV RPDRLEPGVL DRVLGRVTGR GQK
//