ID   E6PGU8_9ZZZZ            Unreviewed;       373 AA.
AC   E6PGU8;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   SubName: Full=Putative D-alanine racemase {ECO:0000313|EMBL:CBH75686.1};
DE            EC=5.1.1.1 {ECO:0000313|EMBL:CBH75686.1};
GN   ORFNames=CARN1_2549 {ECO:0000313|EMBL:CBH75686.1};
OS   mine drainage metagenome.
OC   unclassified sequences; metagenomes; ecological metagenomes.
OX   NCBI_TaxID=410659 {ECO:0000313|EMBL:CBH75686.1};
RN   [1] {ECO:0000313|EMBL:CBH75686.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Bertin P.N., Heinrich-Salmeron A., Pelletier E., Goulhen-Chollet F.,
RA   Arsene-Ploetze F., Gallien S., Calteau A., Vallenet D., Casiot C.,
RA   Chane-Woon-Ming B., Giloteaux L., Barakat M., Bonnefoy V., Bruneel O.,
RA   Chandler M., Cleiss J., Duran R., Elbaz-Poulichet F., Fonknechten N.,
RA   Lauga B., Mornico D., Ortet P., Schaeffer C., Siguier P.,
RA   Alexander Thil Smith A., Van Dorsselaer A., Weissenbach J., Medigue C.,
RA   Le Paslier D.;
RT   "Diversity of trophic interactions inside an arsenic-rich microbial
RT   ecosystem.";
RL   Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CBH75686.1}.
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DR   EMBL; CABL01000014; CBH75686.1; -; Genomic_DNA.
DR   AlphaFoldDB; E6PGU8; -.
DR   GO; GO:0008784; F:alanine racemase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006522; P:alanine metabolic process; IEA:InterPro.
DR   CDD; cd00430; PLPDE_III_AR; 1.
DR   Gene3D; 3.20.20.10; Alanine racemase; 1.
DR   HAMAP; MF_01201; Ala_racemase; 1.
DR   InterPro; IPR000821; Ala_racemase.
DR   InterPro; IPR009006; Ala_racemase/Decarboxylase_C.
DR   InterPro; IPR011079; Ala_racemase_C.
DR   InterPro; IPR001608; Ala_racemase_N.
DR   InterPro; IPR020622; Ala_racemase_pyridoxalP-BS.
DR   InterPro; IPR029066; PLP-binding_barrel.
DR   NCBIfam; TIGR00492; alr; 1.
DR   PANTHER; PTHR30511; ALANINE RACEMASE; 1.
DR   PANTHER; PTHR30511:SF0; ALANINE RACEMASE, CATABOLIC-RELATED; 1.
DR   Pfam; PF00842; Ala_racemase_C; 1.
DR   Pfam; PF01168; Ala_racemase_N; 1.
DR   PRINTS; PR00992; ALARACEMASE.
DR   SMART; SM01005; Ala_racemase_C; 1.
DR   SUPFAM; SSF50621; Alanine racemase C-terminal domain-like; 1.
DR   SUPFAM; SSF51419; PLP-binding barrel; 1.
DR   PROSITE; PS00395; ALANINE_RACEMASE; 1.
PE   3: Inferred from homology;
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:CBH75686.1};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898}.
FT   DOMAIN          243..371
FT                   /note="Alanine racemase C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01005"
SQ   SEQUENCE   373 AA;  39885 MW;  5D0060A684FB8A7C CRC64;
     MNDGLEISLA ALRANADALR ALVAPTHAAF VVKGNAYGHG APEVARAIES HARYLCVYTI
     DEALALRAAG IVAPLLILGP VPAASLRAAL EHDCELPLWD ERGYLHDLAA AARACGKTAR
     VHVKINTGLN RFGIAAEECD ALLDAVESVR NVEIVGVFSH LAAAEEIDSP YTQYQLARFT
     LARERVRARF PAAQQHIAAS AAAMLWPQSR LDIARFGIAL YGLWPSEQTQ AAMRDSGLSL
     RPALSYRSQL VVTREIEAGE AIGYGCTFHA PRAMRIGVLP LGYADGIPRL LSNGGSFLVD
     GARCAILGRI AMNTTVLDLT HAPAAGVGAA VTLIGCDGNE EISADDWARW AQTISYEIVT
     RLPSSLPRTF TEL
//