ID E6PK91_9ZZZZ Unreviewed; 310 AA.
AC E6PK91;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding {ECO:0000313|EMBL:CBH95342.1};
GN ORFNames=CARN2_0732 {ECO:0000313|EMBL:CBH95342.1};
OS mine drainage metagenome.
OC unclassified sequences; metagenomes; ecological metagenomes.
OX NCBI_TaxID=410659 {ECO:0000313|EMBL:CBH95342.1};
RN [1] {ECO:0000313|EMBL:CBH95342.1}
RP NUCLEOTIDE SEQUENCE.
RA Bertin P.N., Heinrich-Salmeron A., Pelletier E., Goulhen-Chollet F.,
RA Arsene-Ploetze F., Gallien S., Calteau A., Vallenet D., Casiot C.,
RA Chane-Woon-Ming B., Giloteaux L., Barakat M., Bonnefoy V., Bruneel O.,
RA Chandler M., Cleiss J., Duran R., Elbaz-Poulichet F., Fonknechten N.,
RA Lauga B., Mornico D., Ortet P., Schaeffer C., Siguier P.,
RA Alexander Thil Smith A., Van Dorsselaer A., Weissenbach J., Medigue C.,
RA Le Paslier D.;
RT "Diversity of trophic interactions inside an arsenic-rich microbial
RT ecosystem.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CBH95342.1}.
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DR EMBL; CABM01000004; CBH95342.1; -; Genomic_DNA.
DR AlphaFoldDB; E6PK91; -.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43333; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43333:SF1; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 104..275
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 310 AA; 34201 MW; E0B75C998E339E57 CRC64;
MPGILFYSLY DDAEAWRAQF ALNFPDWSFH GWPDVEEPDV IEVALVWKPP RGALKASRNL
RLIINLGAGV DAILSDPELP EGVPIVRLND PGMAAMMMQY VLFCVLNYHR NFPEFAQAQK
QRRWHYIHPR PARHTHIGLL GLGMLGGFVA MELSRQGFTV SGWARTPKQI DGIATLHGAR
PPSEWLRTLD VLVVLLPLTP QTRGLVDRTV LQALPRGAKL VSVGRGAVVT EADLIDALRD
GQIGAATVDT CEQEPLPTEH PFWAMENVIL TPHLASVAVP ESCMAQIVRD IEAVRAGQRP
AHVVDPAAGY
//
