ID E6PRZ7_9ZZZZ Unreviewed; 418 AA.
AC E6PRZ7;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Integrase {ECO:0000313|EMBL:CBH97703.1};
GN ORFNames=CARN2_3178 {ECO:0000313|EMBL:CBH97703.1};
OS mine drainage metagenome.
OC unclassified sequences; metagenomes; ecological metagenomes.
OX NCBI_TaxID=410659 {ECO:0000313|EMBL:CBH97703.1};
RN [1] {ECO:0000313|EMBL:CBH97703.1}
RP NUCLEOTIDE SEQUENCE.
RA Bertin P.N., Heinrich-Salmeron A., Pelletier E., Goulhen-Chollet F.,
RA Arsene-Ploetze F., Gallien S., Calteau A., Vallenet D., Casiot C.,
RA Chane-Woon-Ming B., Giloteaux L., Barakat M., Bonnefoy V., Bruneel O.,
RA Chandler M., Cleiss J., Duran R., Elbaz-Poulichet F., Fonknechten N.,
RA Lauga B., Mornico D., Ortet P., Schaeffer C., Siguier P.,
RA Alexander Thil Smith A., Van Dorsselaer A., Weissenbach J., Medigue C.,
RA Le Paslier D.;
RT "Diversity of trophic interactions inside an arsenic-rich microbial
RT ecosystem.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC {ECO:0000256|ARBA:ARBA00008857}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CBH97703.1}.
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DR EMBL; CABM01000047; CBH97703.1; -; Genomic_DNA.
DR AlphaFoldDB; E6PRZ7; -.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW.
DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR GO; GO:0044826; P:viral genome integration into host DNA; IEA:UniProtKB-KW.
DR CDD; cd00801; INT_P4_C; 1.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 3.30.160.390; Integrase, DNA-binding domain; 1.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR038488; Integrase_DNA-bd_sf.
DR InterPro; IPR025166; Integrase_DNA_bind_dom.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR InterPro; IPR004107; Integrase_SAM-like_N.
DR PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR PANTHER; PTHR30629:SF2; PROPHAGE INTEGRASE INTS-RELATED; 1.
DR Pfam; PF13356; Arm-DNA-bind_3; 1.
DR Pfam; PF14659; Phage_int_SAM_3; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Viral genome integration {ECO:0000256|ARBA:ARBA00023195};
KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT DOMAIN 97..176
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000259|PROSITE:PS51900"
FT DOMAIN 199..384
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
FT REGION 74..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 418 AA; 47021 MW; D8D4183F182D2946 CRC64;
MLTDTALKNL KPKDAPYKVT DRDGMYVTVS TVGTVTFRYD YRINSRRETL TIGRYGPGGL
SLARAREKCI DAKRAVTEGQ SPAQEKQREK RRLSEAQTFQ EFTDKWYEGA RMADSTRSMR
KSILDRDILP VFKSRLLSEI SPDDLRDLCN KVKGRGAPAT AIHVRDIIKQ IYGFAILHGE
KVANPADGVG PSSIATFVPR DRALSPTEIH ILLKQLEYVA SYPTIKLGLR LILLTLVRKG
ELIHATWDEI DFENALWTIP KARMKAAKAH NIYLSQQALD IMIALRTCAG GSKYLLPSRY
DGDKCMSNAT LNRVAQIVVE RSKAKGLPIE SFSVHDLRRT GSTILNELGF NSDWIEKCLA
HEDGRSSRGV YNKAEYAEQR RHMLQEWADM VDAWVAGESH TPTLLPPSMK IITTQALL
//
