ID E6QN31_9ZZZZ Unreviewed; 473 AA.
AC E6QN31;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Protoporphyrinogen oxidase {ECO:0000313|EMBL:CBI08652.1};
DE EC=1.3.3.4 {ECO:0000313|EMBL:CBI08652.1};
GN ORFNames=CARN6_2138 {ECO:0000313|EMBL:CBI08652.1};
OS mine drainage metagenome.
OC unclassified sequences; metagenomes; ecological metagenomes.
OX NCBI_TaxID=410659 {ECO:0000313|EMBL:CBI08652.1};
RN [1] {ECO:0000313|EMBL:CBI08652.1}
RP NUCLEOTIDE SEQUENCE.
RA Bertin P.N., Heinrich-Salmeron A., Pelletier E., Goulhen-Chollet F.,
RA Arsene-Ploetze F., Gallien S., Calteau A., Vallenet D., Casiot C.,
RA Chane-Woon-Ming B., Giloteaux L., Barakat M., Bonnefoy V., Bruneel O.,
RA Chandler M., Cleiss J., Duran R., Elbaz-Poulichet F., Fonknechten N.,
RA Lauga B., Mornico D., Ortet P., Schaeffer C., Siguier P.,
RA Alexander Thil Smith A., Van Dorsselaer A., Weissenbach J., Medigue C.,
RA Le Paslier D.;
RT "Diversity of trophic interactions inside an arsenic-rich microbial
RT ecosystem.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- PATHWAY: Porphyrin-containing compound metabolism.
CC {ECO:0000256|ARBA:ARBA00023444}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CBI08652.1}.
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DR EMBL; CABQ01000246; CBI08652.1; -; Genomic_DNA.
DR AlphaFoldDB; E6QN31; -.
DR GO; GO:0004729; F:oxygen-dependent protoporphyrinogen oxidase activity; IEA:UniProtKB-EC.
DR GO; GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 1.10.3110.10; protoporphyrinogen ix oxidase, domain 3; 1.
DR InterPro; IPR002937; Amino_oxidase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR004572; Protoporphyrinogen_oxidase.
DR NCBIfam; TIGR00562; proto_IX_ox; 1.
DR PANTHER; PTHR42923; PROTOPORPHYRINOGEN OXIDASE; 1.
DR PANTHER; PTHR42923:SF3; PROTOPORPHYRINOGEN OXIDASE; 1.
DR Pfam; PF01593; Amino_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Heme biosynthesis {ECO:0000256|ARBA:ARBA00023133};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:CBI08652.1}.
FT DOMAIN 10..470
FT /note="Amine oxidase"
FT /evidence="ECO:0000259|Pfam:PF01593"
SQ SEQUENCE 473 AA; 51157 MW; BD8277FD5EE56DF9 CRC64;
MRVAILGGGI AGLSAAYELE LARRRGSGTD YVLFEASPRL GGVISSQVAN GCVLEHGPDS
FLTEKPAALE LCRELGLESD LIPSNDTERK TFILVRNRLI ALPDGLMFLV PTKLVPAALT
PLFSLGTKLR MALEYFKPVR PGFGDESVAD LVRRHYGQEV VDRLADPLLS GIYGGDATQL
SAQSVLPRLV QMEAQYGSLT RGMLASRKNM QTAQHTQKTS SAAPRPIFTT LRGGLRQMID
VLAAQLEPSR IRCSTTVRSI TRGASGWQLS LSETELRGSA VEDFDAVIVA TPAWAAAQFL
GGSHPALSAE LDGIPYSSSI TMNLVFDEAF LGQLPEGFGF LVPAVERRAI LACTFVHRKF
PGRTAPGKAV LRVFLGGARN EPLLAESDDA LTGIVREELR QMLGIAAQPE LVQVRRWRRA
MAQYAVGHAG RQQRIRAHLE TLPGLHLVGN AYDGIGIADC IRLGRQAARA TQK
//
