ID E6QU32_9ZZZZ Unreviewed; 789 AA.
AC E6QU32;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 13-SEP-2023, entry version 24.
DE SubName: Full=DNA internalization-related competence protein ComEC/Rec2 {ECO:0000313|EMBL:CBI10754.1};
GN ORFNames=CARN7_1549 {ECO:0000313|EMBL:CBI10754.1};
OS mine drainage metagenome.
OC unclassified sequences; metagenomes; ecological metagenomes.
OX NCBI_TaxID=410659 {ECO:0000313|EMBL:CBI10754.1};
RN [1] {ECO:0000313|EMBL:CBI10754.1}
RP NUCLEOTIDE SEQUENCE.
RA Bertin P.N., Heinrich-Salmeron A., Pelletier E., Goulhen-Chollet F.,
RA Arsene-Ploetze F., Gallien S., Calteau A., Vallenet D., Casiot C.,
RA Chane-Woon-Ming B., Giloteaux L., Barakat M., Bonnefoy V., Bruneel O.,
RA Chandler M., Cleiss J., Duran R., Elbaz-Poulichet F., Fonknechten N.,
RA Lauga B., Mornico D., Ortet P., Schaeffer C., Siguier P.,
RA Alexander Thil Smith A., Van Dorsselaer A., Weissenbach J., Medigue C.,
RA Le Paslier D.;
RT "Diversity of trophic interactions inside an arsenic-rich microbial
RT ecosystem.";
RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CBI10754.1}.
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DR EMBL; CABR01000103; CBI10754.1; -; Genomic_DNA.
DR AlphaFoldDB; E6QU32; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..384
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 420..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..472
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 478..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 502..526
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 533..726
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 789 AA; 86056 MW; 36E89B8DEA47F797 CRC64;
MTQTLSWRAA IVAFVVGVMG VQQLAQLPQP YWLWGMPLLA SVWALPRQGG WRVARLTGFL
LCWIALGVAW ATWRADLRLA DNLPATWAGV PVMVSGVVSD LPVRTDRGQH FEFNVDRVLT
PGAQVPSSIQ LSLYSAHSAG APAAPPVQVG QCWQWMVRLN RPHASQNPHV MDMESVRFAN
DVRAMGVVGT RPQPQLLAAW VNSPMNRINL MREDIAQRID RALPNQPYAG VLKALTVGDQ
SAIPAAQWQL FQRTGIVHLI SISGSHITML AGLAYFVCFW SWRRIPRLSL WLPAQRAATL
AGALTALAYV ALAGFGIPAQ RTLLMLAVAA WALWTGRTLA PTRVLAAALF AVVLLDPWAV
LSPGFWLSFG AVGLLMFSAG ARVGEVHWLQ AWWRSQWAVT MGMAPVLLLL FGQLSTVSPL
ANVVAIPAIE FVITPVALLG SIPGLGILLH VAHAGMSALV WLLQILATWP LWQQAEPSPF
VVGLAMLGAL WWLLPRGFPA RWLGAFCLLP ALLVQAPVPA TGAMWVETLD IGQGLAVLVR
TAHHNYLFDT GPRYGPNSDS GGRIILPYLR GEGVTQLDTL VLSHDDNDHT GGAGSILAAM
PVDKILTPLP TDHVLIKPYV QHYLRCETGL SWAVDGVNFH VLHPDVSSYA DPTLKDNHRG
CVLKVDSPGG SVLLTADIEA PDEAYLLQHP ADLPSDLLLA PHHGSHTSST PAFITAVHPK
WVIFTVGAHN RFGHPHGDVV ARYANQGIAM WRSDWNGEVS FHFTPKQAPT MLAWRQAHQR
YWMDGASEE
//
