ID E6QYV5_CRYGW Unreviewed; 423 AA.
AC E6QYV5;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 22-FEB-2023, entry version 51.
DE SubName: Full=Racemase, putative {ECO:0000313|EMBL:ADV19300.1};
GN OrderedLocusNames=CGB_A0030W {ECO:0000313|EMBL:ADV19300.1};
OS Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071)
OS (Filobasidiella gattii) (Cryptococcus bacillisporus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus gattii species complex.
OX NCBI_TaxID=367775 {ECO:0000313|EMBL:ADV19300.1, ECO:0000313|Proteomes:UP000007805};
RN [1] {ECO:0000313|EMBL:ADV19300.1, ECO:0000313|Proteomes:UP000007805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM276 / ATCC MYA-4071 {ECO:0000313|Proteomes:UP000007805};
RX PubMed=21304167; DOI=10.1128/mBio.00342-10;
RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA Schein J., Krzywinski M., Kwon-Chung K.J., Varma A., Wang J., Brunham R.,
RA Fyfe M., Ouellette B.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA Birren B.W., Galagan J.E., Cuomo C.A.;
RT "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT immunocompetent hosts.";
RL MBio 2:E342-E342(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WM276;
RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA Schein J., Krzywinski M., Kwong-Chung K.J., Varma A., Wang J., Brunham R.,
RA Fyfe M., Ouellette B.F.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA Birren B.W., Galagan J.E., Cuomo C.A.;
RT "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT immunocompetent hosts.";
RL MBio 0:0-0(2011).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR EMBL; CP000286; ADV19300.1; -; Genomic_DNA.
DR RefSeq; XP_003191087.1; XM_003191039.1.
DR AlphaFoldDB; E6QYV5; -.
DR GeneID; 10188709; -.
DR KEGG; cgi:CGB_A0030W; -.
DR VEuPathDB; FungiDB:CGB_A0030W; -.
DR eggNOG; ENOG502QRKX; Eukaryota.
DR HOGENOM; CLU_030273_1_1_1; -.
DR OrthoDB; 33243at2759; -.
DR Proteomes; UP000007805; Chromosome A.
DR GO; GO:0050032; F:L-rhamnonate dehydratase activity; IEA:InterPro.
DR CDD; cd03327; MR_like_2; 1.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR029065; Enolase_C-like.
DR InterPro; IPR023444; L-Rhamnon_dehydrat.
DR InterPro; IPR013342; Mandelate_racemase_C.
DR InterPro; IPR013341; Mandelate_racemase_N_dom.
DR InterPro; IPR046945; RHMD-like.
DR PANTHER; PTHR13794; ENOLASE SUPERFAMILY, MANDELATE RACEMASE; 1.
DR PANTHER; PTHR13794:SF58; MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1; 1.
DR Pfam; PF13378; MR_MLE_C; 1.
DR Pfam; PF02746; MR_MLE_N; 1.
DR SFLD; SFLDG00179; mandelate_racemase; 1.
DR SFLD; SFLDF00006; rhamnonate_dehydratase; 1.
DR SMART; SM00922; MR_MLE; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
PE 4: Predicted;
FT DOMAIN 170..268
FT /note="Mandelate racemase/muconate lactonizing enzyme C-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00922"
SQ SEQUENCE 423 AA; 46790 MW; 4D4CA69E79A60A3B CRC64;
MPKQWPTIVK LETFIPSAHG SGGDYHRQGG DHWIVQGNIS CPMHKYEEYK VSRTSWGIGV
LGSIFVKVHA SDGTVGYATG FGGPPACWLI EEHFKRFIVG QDPRDTNKMW DQMFRASMFY
GRKGLPLAAI SVVDLAIWDL LGKIRGEPVY KMIGGRTKKD IPLYLTGPRP EVAKKLGFWG
SKVALPHGPP DGHEGIRKNV QYLKACKEAV GPDYPVQVDC YMSLDVPYTI ALIKACEKAG
VEINWWEEVL HPDDFDGHVK LKEALPYVKF TTGEHEYSKY GFRKLIENRA VDIIQPDVMW
LGGLTELIKV AAMAAAYDIP VVPHGSGPYS FQAIMSFPNS DFCEYIANSP DGKSIEPSFG
NLFLNEVLPH NGRIDLTDEP GFGLELNPSA ELVPYKSFFT PSKGLGAAGE VEDDGKAKVN
GTH
//
