ID E6S7G5_INTC7 Unreviewed; 312 AA.
AC E6S7G5;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Dihydropteroate synthase {ECO:0000313|EMBL:ADU46860.1};
DE EC=2.5.1.15 {ECO:0000313|EMBL:ADU46860.1};
GN OrderedLocusNames=Intca_0305 {ECO:0000313|EMBL:ADU46860.1};
OS Intrasporangium calvum (strain ATCC 23552 / DSM 43043 / JCM 3097 / NBRC
OS 12989 / 7 KIP).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Intrasporangium.
OX NCBI_TaxID=710696 {ECO:0000313|EMBL:ADU46860.1, ECO:0000313|Proteomes:UP000008914};
RN [1] {ECO:0000313|EMBL:ADU46860.1, ECO:0000313|Proteomes:UP000008914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23552 / DSM 43043 / JCM 3097 / NBRC 12989 / 7 KIP
RC {ECO:0000313|Proteomes:UP000008914};
RX PubMed=21304734; DOI=10.4056/sigs.1263355;
RA Del Rio T.G., Chertkov O., Yasawong M., Lucas S., Deshpande S., Cheng J.F.,
RA Detter C., Tapia R., Han C., Goodwin L., Pitluck S., Liolios K.,
RA Ivanova N., Mavromatis K., Pati A., Chen A., Palaniappan K., Land M.,
RA Hauser L., Chang Y.J., Jeffries C.D., Rohde M., Pukall R., Sikorski J.,
RA Goker M., Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.P., Lapidus A.;
RT "Complete genome sequence of Intrasporangium calvum type strain (7 KIP).";
RL Stand. Genomic Sci. 3:294-303(2010).
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DR EMBL; CP002343; ADU46860.1; -; Genomic_DNA.
DR AlphaFoldDB; E6S7G5; -.
DR STRING; 710696.Intca_0305; -.
DR KEGG; ica:Intca_0305; -.
DR eggNOG; COG0294; Bacteria.
DR HOGENOM; CLU_008023_0_0_11; -.
DR OrthoDB; 9811744at2; -.
DR Proteomes; UP000008914; Chromosome.
DR GO; GO:0004156; F:dihydropteroate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009396; P:folic acid-containing compound biosynthetic process; IEA:InterPro.
DR Gene3D; 3.20.20.20; Dihydropteroate synthase-like; 1.
DR InterPro; IPR045031; DHP_synth-like.
DR InterPro; IPR006390; DHP_synth_dom.
DR InterPro; IPR011005; Dihydropteroate_synth-like_sf.
DR InterPro; IPR000489; Pterin-binding_dom.
DR NCBIfam; TIGR01496; DHPS; 1.
DR PANTHER; PTHR20941; FOLATE SYNTHESIS PROTEINS; 1.
DR PANTHER; PTHR20941:SF8; INACTIVE DIHYDROPTEROATE SYNTHASE 2; 1.
DR Pfam; PF00809; Pterin_bind; 1.
DR SUPFAM; SSF51717; Dihydropteroate synthetase-like; 1.
DR PROSITE; PS50972; PTERIN_BINDING; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008914};
KW Transferase {ECO:0000313|EMBL:ADU46860.1}.
FT DOMAIN 27..285
FT /note="Pterin-binding"
FT /evidence="ECO:0000259|PROSITE:PS50972"
SQ SEQUENCE 312 AA; 33064 MW; DC0179FFA9646A8F CRC64;
MSGLRPVDPV PAPPLVLRGR TFDAGRPAVM AIVNRTPDSF FGGNRHADLD SAKRALEEAL
ALGADIIDVG GVRAGQEGEP VDEDEEVRRV VPFLEWARRA HPDVILSLDT WRSGVALAAA
GAGVDMVNDT WAGADPDLVR VAARLGAGYV ISHTGGLPPR TDPVAVTYGD DPLDVVRDVV
TTLADGARAA ELSGIPPERI LVDPTLDFGK TTMHSLEVLR HTADVAALGY PVLQALSRKD
FVGESLDVPV EDRLEGSLAA TAVAAWLGAT VFRAHDVRAT RRVVDMVATI RGDRPPVHAR
RGTPQTGSAN SR
//
