ID E6S8U4_INTC7 Unreviewed; 599 AA.
AC E6S8U4;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE RecName: Full=DNA repair protein RecN {ECO:0000256|ARBA:ARBA00021315, ECO:0000256|PIRNR:PIRNR003128};
DE AltName: Full=Recombination protein N {ECO:0000256|ARBA:ARBA00033408, ECO:0000256|PIRNR:PIRNR003128};
GN OrderedLocusNames=Intca_1568 {ECO:0000313|EMBL:ADU48081.1};
OS Intrasporangium calvum (strain ATCC 23552 / DSM 43043 / JCM 3097 / NBRC
OS 12989 / 7 KIP).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Intrasporangium.
OX NCBI_TaxID=710696 {ECO:0000313|EMBL:ADU48081.1, ECO:0000313|Proteomes:UP000008914};
RN [1] {ECO:0000313|EMBL:ADU48081.1, ECO:0000313|Proteomes:UP000008914}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 23552 / DSM 43043 / JCM 3097 / NBRC 12989 / 7 KIP
RC {ECO:0000313|Proteomes:UP000008914};
RX PubMed=21304734; DOI=10.4056/sigs.1263355;
RA Del Rio T.G., Chertkov O., Yasawong M., Lucas S., Deshpande S., Cheng J.F.,
RA Detter C., Tapia R., Han C., Goodwin L., Pitluck S., Liolios K.,
RA Ivanova N., Mavromatis K., Pati A., Chen A., Palaniappan K., Land M.,
RA Hauser L., Chang Y.J., Jeffries C.D., Rohde M., Pukall R., Sikorski J.,
RA Goker M., Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.P., Lapidus A.;
RT "Complete genome sequence of Intrasporangium calvum type strain (7 KIP).";
RL Stand. Genomic Sci. 3:294-303(2010).
CC -!- FUNCTION: May be involved in recombinational repair of damaged DNA.
CC {ECO:0000256|ARBA:ARBA00003618, ECO:0000256|PIRNR:PIRNR003128}.
CC -!- SIMILARITY: Belongs to the RecN family. {ECO:0000256|ARBA:ARBA00009441,
CC ECO:0000256|PIRNR:PIRNR003128}.
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DR EMBL; CP002343; ADU48081.1; -; Genomic_DNA.
DR AlphaFoldDB; E6S8U4; -.
DR STRING; 710696.Intca_1568; -.
DR KEGG; ica:Intca_1568; -.
DR eggNOG; COG0497; Bacteria.
DR HOGENOM; CLU_018297_3_0_11; -.
DR Proteomes; UP000008914; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR004604; DNA_recomb/repair_RecN.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR NCBIfam; TIGR00634; recN; 1.
DR PANTHER; PTHR11059; DNA REPAIR PROTEIN RECN; 1.
DR PANTHER; PTHR11059:SF0; DNA REPAIR PROTEIN RECN; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF003128; RecN; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|PIRNR:PIRNR003128};
KW DNA repair {ECO:0000256|PIRNR:PIRNR003128};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008914}.
FT DOMAIN 14..546
FT /note="RecF/RecN/SMC N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02463"
FT COILED 344..378
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 599 AA; 62537 MW; D6C85C5C1E3F0756 CRC64;
MFSEMRIRGV GVIHDAVLDL SPGLNVLTGE TGAGKTMVVS GLGLLLGERA DSSLVRSGAD
QAFVEGVVQL PPGHPALDRA AEAGAEHDDG ELVIARTLSA SGRSRAHVGG RTAPVGVLAE
LGRHLVAVHG QADQWRLKQG DAHREVLDGF GGPALGALRD RVGRLHDEWR GAHAEHDRLV
AESRERAREI DSLTAALEEI EAVDPQPGED LSLRAEDERL AHDDSLRLAA ARALADLSGE
EYAAEPAPSV RDLVGSARSA LGHGAVHDSR LGDLDARLDE VAALVGDVAA DLTAYLEDVD
LDPQRLEFVQ ERRAALAGLT RKYGETVDEV LDWSQQAAAR LDALVSADDR VESLRSQLDE
LTAELAAAAS DLSAARAAAG ADFAARVSGE LAHLSMGKAV IEVRVEQRPA GDGILMASGE
RVRISRLGAD DVEILLSANP GATPRSVAKA ASGGELSRVM LALEVVGASP LAQGRPGSQP
QPRAGTPPTF VFDEVDAGVG GRAALDVGAR LAALAQQAQV IVVTHLAQVA AFADRHLVVH
KSDDGAITSS SITVVDGEER LRELSRMMGG DPDSEAGLAH ARDLLEQTAA ARVSRVGAA
//
