ID   E6TBR8_MYCSR            Unreviewed;       731 AA.
AC   E6TBR8;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   27-MAR-2024, entry version 72.
DE   SubName: Full=ATP-dependent transcriptional regulator {ECO:0000313|EMBL:ADU00780.1};
GN   OrderedLocusNames=Mspyr1_42190 {ECO:0000313|EMBL:ADU00780.1};
OS   Mycolicibacterium gilvum (strain DSM 45189 / LMG 24558 / Spyr1)
OS   (Mycobacterium gilvum).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=278137 {ECO:0000313|EMBL:ADU00780.1, ECO:0000313|Proteomes:UP000008916};
RN   [1] {ECO:0000313|Proteomes:UP000008916}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45189 / LMG 24558 / Spyr1
RC   {ECO:0000313|Proteomes:UP000008916};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., LaButti K., Ivanova N.M., Mikhailova N.M., Land M., Hauser L.,
RA   Koukkou A.I., Drainas C., Kyrpides N., Woyke T.;
RT   "Complete sequence of chromosome of Mycobacterium sp. Spyr1.";
RL   Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADU00780.1, ECO:0000313|Proteomes:UP000008916}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45189 / LMG 24558 / Spyr1
RC   {ECO:0000313|Proteomes:UP000008916};
RX   PubMed=22180818;
RA   Kallimanis A., Karabika E., Mavromatis K., Lapidus A., Labutti K.M.,
RA   Liolios K., Ivanova N., Goodwin L., Woyke T., Velentzas A.D.,
RA   Perisynakis A., Ouzounis C.C., Kyrpides N.C., Koukkou A.I., Drainas C.;
RT   "Complete genome sequence of Mycobacterium sp. strain (Spyr1) and
RT   reclassification to Mycobacterium gilvum Spyr1.";
RL   Stand. Genomic Sci. 5:144-153(2011).
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DR   EMBL; CP002385; ADU00780.1; -; Genomic_DNA.
DR   AlphaFoldDB; E6TBR8; -.
DR   KEGG; msp:Mspyr1_42190; -.
DR   HOGENOM; CLU_006325_2_0_11; -.
DR   Proteomes; UP000008916; Chromosome.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF13401; AAA_22; 1.
DR   Pfam; PF00196; GerE; 1.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125}.
FT   DOMAIN          662..727
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50043"
SQ   SEQUENCE   731 AA;  77832 MW;  5A9FD93F4B5A5A26 CRC64;
     MVAGDWRPHV PAVTMGRPRI ADRVIPRPEL VKRLGSAVGG DLVVLTAPAG YGKTTAAALW
     DAEDDRQFAW ARIDHLDDDP GHLLLHIATA VVRLGAGDEH LLNYLRGPGR EPEQLLPAVV
     RLLEEFGPIV VILDDVHKLS APQSVSTLHA LVDAAPLTTT VALLGRFLLP LDIARRRLAG
     NLVEVDQDAL RLTAEETVAA LESVRGPSDD ATVATVIDLC EGWAAGVILT AMALRDGTAP
     EALAGRNNLV VEYVVEEVID RVDDDTRSFL LESAMLDRFT AEHLDAVLGR VDAAWMLEQL
     ATSGNPFLIS LDSQGDSFRY HHLFGDVLRA RLRASEPARF RELASCAADL LEREGDIDGA
     LVHALEAGDR ARAAALVGRE AVRLGFDGRA GVLARRLGML DARTFAEQPD AAVARAWLGV
     TTADAELIQR SLMLALHSDH GGPLADGTPS VSVAVALISS LVGVGGVAEV IRHADTVRAA
     GDNLVNPWWG AATVMKGAAE AMRGQGGRAR LLLESALPVI EDLPGFHAAA LAHLALLDLA
     AGDDEAAVER CDAARTLADK YDLSDVVPMI VVYSTSAVMS ARVGDVPAAL HAVQITQTLL
     ERLGNLSART ALLGHGLLAW TAAALQDRAL LSRHLTAAER VRHREPDAVA LVQRVERVKA
     MAVGGTRPLT AAELRLLPHL ATHLSLQRIA EELVIGRETA KSQATSIYRK LGVSSRGQAV
     SEAIRIGLLA D
//