ID E6TEP1_MYCSR Unreviewed; 504 AA.
AC E6TEP1;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Predicted Zn-dependent protease-like protein {ECO:0000313|EMBL:ADT98823.1};
GN OrderedLocusNames=Mspyr1_21700 {ECO:0000313|EMBL:ADT98823.1};
OS Mycolicibacterium gilvum (strain DSM 45189 / LMG 24558 / Spyr1)
OS (Mycobacterium gilvum).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=278137 {ECO:0000313|EMBL:ADT98823.1, ECO:0000313|Proteomes:UP000008916};
RN [1] {ECO:0000313|Proteomes:UP000008916}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45189 / LMG 24558 / Spyr1
RC {ECO:0000313|Proteomes:UP000008916};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., LaButti K., Ivanova N.M., Mikhailova N.M., Land M., Hauser L.,
RA Koukkou A.I., Drainas C., Kyrpides N., Woyke T.;
RT "Complete sequence of chromosome of Mycobacterium sp. Spyr1.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADT98823.1, ECO:0000313|Proteomes:UP000008916}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 45189 / LMG 24558 / Spyr1
RC {ECO:0000313|Proteomes:UP000008916};
RX PubMed=22180818;
RA Kallimanis A., Karabika E., Mavromatis K., Lapidus A., Labutti K.M.,
RA Liolios K., Ivanova N., Goodwin L., Woyke T., Velentzas A.D.,
RA Perisynakis A., Ouzounis C.C., Kyrpides N.C., Koukkou A.I., Drainas C.;
RT "Complete genome sequence of Mycobacterium sp. strain (Spyr1) and
RT reclassification to Mycobacterium gilvum Spyr1.";
RL Stand. Genomic Sci. 5:144-153(2011).
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
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DR EMBL; CP002385; ADT98823.1; -; Genomic_DNA.
DR RefSeq; WP_011893612.1; NC_014814.1.
DR AlphaFoldDB; E6TEP1; -.
DR KEGG; msp:Mspyr1_21700; -.
DR HOGENOM; CLU_026425_1_2_11; -.
DR Proteomes; UP000008916; Chromosome.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR30624:SF10; CONSERVED PROTEIN; 1.
DR PANTHER; PTHR30624; UNCHARACTERIZED PROTEIN TLDD AND PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:ADT98823.1}.
FT DOMAIN 34..98
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 255..495
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 504 AA; 54533 MW; 4908A6A802079357 CRC64;
MTARTVDADF LALPRHALAD AALTAAVQAG AGYADLRIHA ITTETVQLRD GALETAVTDY
EIGLAVRVIV DGTWGFASHA QLDTAAAADT ARRAVRVATR LAALNAERIE LAPEPVYRDV
SWVSDYRIDP FAVPTQDKIE VLEDYSGRLL ASEGIDHVSA WLNMAKEQTF YADTFGSTIT
QQRVRVLPRC DAVTVDPAAG SFETMSTLAP PMGRGWEAVV GNEVWDWAGE LAELPTLLAE
KAKAPSVIAG PKDLVIDPTN LWLTIHESIG HATEYDRAIG YEAAYAGTSF ATPDKLGRLR
YGSSVMNVTA DRTVEHGLAT VGFDDEGVRA QSWDLVRDGL FVGYQLDRVF APRLGVGRSN
GCSYADSAQH VPIQRMANVS LQPAPEDVST EELIGRVSDG LYIVGDKSWS IDMQRYNFQF
TGQRFFKITD GRLDGQVRDV AYQATTTDFW GALEAVGGPS TWRLGGAFNC GKAQPGQVAA
VSHGCPSALF RGVNILNTRE ESGR
//
